DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Arp3 and acta2

DIOPT Version :9

Sequence 1:	NP_001261559.1	Gene:	Arp3 / 38898	FlyBaseID:	FBgn0262716	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_997785.2	Gene:	acta2 / 322509	ZFINID:	ZDB-GENE-030131-1229	Length:	377	Species:	Danio rerio

Alignment Length:	419	Identity:	154/419 - (36%)
Similarity:	215/419 - (51%)	Gaps:	61/419 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ACVIDVGTGYSKLGFAGNKEPQFIIPSAIAIKESARVGDTNTRRITKGIEDLDFFIGDEAFDATG 71
            |.|.|.|:|..|.||||:..|:.:.||.        ||....:.:..|:...|.::||||....|
Zfish     9 ALVCDNGSGLCKAGFAGDDAPRAVFPSI--------VGRPRHQGVMVGMGQKDSYVGDEAQSKRG 65

  Fly    72 -YSIKYPVRHGLVEDWDLMERFLEQCVFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFETFN 135
             .::|||:.||::.:||.||:......:..||..||:|..||||.|||...|||...:|||||||
Zfish    66 ILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFN 130

  Fly   136 VPGLYIAVQAVLALAASWASRSAEERTLTGIVVDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRNI 200
            ||.:|:|:||||:|.||       .|| ||||:||||||||.:|:.|||.:...|..:.:|||::
Zfish   131 VPAMYVAIQAVLSLYAS-------GRT-TGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDL 187

  Fly   201 TSFIQSLLREREVGIPPEQSLETAKAIKEKHCYICPDIAKEFA----------KYDTEPGKWIRN 255
            |.::..:|.||..........|..:.||||.||:..|...|.|          .|:...|:.|
Zfish   188 TDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVI-- 250

  Fly   256 FSGVNTVTKAPFNVDVGYERFLGPEIFFHPEFSNPDFTIPLSEIVDNVIQNCPIDVRRPLYNNIV 320
                          .:|.|||..||..|.|.|...: :..:.|...|.|..|.||:|:.||.|.|
Zfish   251 --------------TIGNERFRCPETLFQPSFIGME-SAGIHETTYNSIMKCDIDIRKDLYANNV 300

  Fly   321 LSGGSTMFKDFGRRLQRDIKRSVDTRLRISENLSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLA 385
            ||||:||:.....|:|::|.                .:.|..:.:::|....::|:||.|||:||
Zfish   301 LSGGTTMYPGIADRMQKEIT----------------ALAPSTMKIKIIAPPERKYSVWIGGSILA 349

  Fly   386 STPEFYQVCHTKAAYEEYGPSICRHNPVF 414
            |...|.|:..:|..|:|.||||. |...|
Zfish   350 SLSTFQQMWISKQEYDEAGPSIV-HRKCF 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_001261559.1	PTZ00280	2..417	CDD:240343	154/419 (37%)
acta2	NP_997785.2	PTZ00281	4..377	CDD:173506	153/417 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920