DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp3 and Actl9b

DIOPT Version :9

Sequence 1:	NP_001261559.1	Gene:	Arp3 / 38898	FlyBaseID:	FBgn0262716	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001013915.1	Gene:	Actl9b / 292516	RGDID:	1359476	Length:	411	Species:	Rattus norvegicus

Alignment Length:	404	Identity:	121/404 - (29%)
Similarity:	205/404 - (50%)	Gaps:	41/404 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RLPACVIDVGTGYSKLGFAGNKEPQFIIPSAIAIKESARVGDTNTRRITKGIEDLDFFIGDEAFD 68
            ::...|||:|||..|:||||...|.:|:.:.        ||....||.|.....::.|||:.|..
  Rat    43 KMSGVVIDMGTGICKMGFAGQTRPTYIVRNI--------VGCQPKRRTTMEQPKMEMFIGEAAHA 99

  Fly    69 ATGYSIKYPVRHGLVEDWDLMERFLEQCVFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFET 133
            ....::.:|||:|:|.||:..|......:...||.:.:||..|.|:||.|...|||...|:.||:
  Rat   100 RPELTLMHPVRNGIVVDWEAAEFIWRHILENDLRLDTQDHPLLFTDPPFNPASNREKLVEVAFES 164

  Fly   134 FNVPGLYIAVQAVLALAASWASRSAEERTLTGIVVDSGDGVTHVIPVAEGYVIGSCIKHIPIAGR 198
            .:.|.:|:|.|:||::.|:        ..:.|:|||:|.||::.:||.:||.:.|.|:.:.:||.
  Rat   165 LHSPAIYVASQSVLSVYAN--------GRVNGLVVDTGHGVSYTVPVFQGYNLPSGIQRMDLAGH 221

  Fly   199 NITSFIQSLLREREVGIPPEQSLETAKAIKEKHCYICPDIAKEFAKYDTEPGKWIRNFSGVNTVT 263
            .:|.|:...:......:..| .::|.:.||:::||:..|..||..:.|.:..:.::...|.
  Rat   222 YLTKFLAEKILRSSFAVKKE-DMDTMENIKQQYCYVALDFQKEQGRPDEKFRRCLKLPDGQ---- 281

  Fly   264 KAPFNVDVGYERFLGPEIFFHPEFSNPDFTIPLSEIVDNVIQNCPIDVRRPLYNNIVLSGGSTMF 328
                .:.||.|.|..||:.|||..::...::.|..:|::.:...|.::|..:..|::|.|||::|
  Rat   282 ----MITVGKELFQCPELLFHPPDTSGPSSLGLPSMVEHSLSTVPQELRADMEQNVLLCGGSSLF 342

  Fly   329 KDFGRRLQRDIKRSVDTRLRISENLSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQV 393
            ..|..|.:.::.|               |:.|: ..|.|:....:..:||.|||:|||...|...
  Rat   343 TGFEGRFKTELLR---------------RLGPE-AHVVVVAQANRNLSVWIGGSILASLCAFQTR 391

  Fly   394 CHTKAAYEEYGPSI 407
            ...:..|||:||.|
  Rat   392 WVLREQYEEHGPDI 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_001261559.1	PTZ00280	2..417	CDD:240343	121/404 (30%)
Actl9b	NP_001013915.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23
		NBD_sugar-kinase_HSP70_actin	45..410	CDD:302596	121/402 (30%)
		Actin	47..411	CDD:278451	121/400 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910