Protein Alignment Arp3 and ACTRT2

DIOPT Version :9

• Sequence 1: NP_001261559.1
• Gene: Arp3 / 38898
• FlyBaseID: FBgn0262716
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_536356.3
• Gene: ACTRT2 / 140625
• HGNCID: 24026
• Length: 377
• Species: Homo sapiens
• Alignment Length: 411
• Identity: 127/411 - (30%)
• Similarity: 200/411 - (48%)
• Gaps: 58/411 - (14%)

  Fly     6 PACVIDVGTGYSKLGFAGNKEPQFIIPSAIA-IKESARVGDTNTRRITKGIEDLDFFIGDEA-FD 68
            ||.:.|.|:|:.|.|.:|...|:.::.|.:. :|..|...:.|.::         :|:|:|| :.
Human    10 PAVIFDNGSGFCKAGLSGEFGPRHMVSSIVGHLKFQAPSAEANQKK---------YFVGEEALYK 65

  Fly    69 ATGYSIKYPVRHGLVEDWDLMERFLEQCVFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFET 133
            .....:..|...||:..||.:||..:......|..:|.|...|.|||.||..||||..||:|||.
Human    66 QEALQLHSPFERGLITGWDDVERLWKHLFEWELGVKPSDQPLLATEPSLNPRENREKMAEVMFEN 130

  Fly   134 FNVPGLYIAVQAVLALAASWASRSAEERTLTGIVVDSGDGVTHVIPVAEGYVIGSCIKHIPIAGR 198
            |.||..|::.||||||.||        ..:||:||||||.||..:|:.|||.:...:..:.:|||
Human   131 FGVPAFYLSDQAVLALYAS--------ACVTGLVVDSGDAVTCTVPIFEGYSLPHAVTKLHVAGR 187

  Fly   199 NITSFIQSLLREREVGIPPEQSLETAKAIKEKHCYICPDIAKEFAKYDTEPGKWIRNFSGVNTVT 263
            :||..:..||.......|.:........||:|.||:..:..||.::   .|.:.:|.:
Human   188 DITELLMQLLLASGHTFPCQLDKGLVDDIKKKLCYVALEPEKELSR---RPEEVLREY------- 242

  Fly   264 KAPFN--VDVGYERFLGPEIFFHPE---FSNPDFTIPLSEIVDNVIQNCPIDVRRPLYNNIVLSG 323
            |.|..  :.:|......||..|.|:   ..:|.    ||.:|.:.|..|..|:::.|:..|||||
Human   243 KLPDGNIISLGDPLHQAPEALFVPQQLGSQSPG----LSNMVSSSITKCDTDIQKILFGEIVLSG 303

  Fly   324 GSTMFKDFGRRLQRDIKR--SVDTRLRISENLSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLAS 386
            |:|:|.....||.:::::  |.||.::|:          .|.|        :.::.|.|.|::.|
Human   304 GTTLFHGLDDRLLKELEQLASKDTPIKIT----------APPD--------RWFSTWIGASIVTS 350

  Fly   387 TPEFYQVCHTKAAYEEYGPSI 407
            ...|.|:..|.|.::|:|.|:
Human   351 LSSFKQMWVTAADFKEFGTSV 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_001261559.1	PTZ00280	2..417	CDD:240343	127/411 (31%)
ACTRT2	NP_536356.3	ACTIN	10..377	CDD:214592	127/411 (31%)
		NBD_sugar-kinase_HSP70_actin	11..377	CDD:302596	126/410 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810