Protein Alignment Arp3 and ACTR2

DIOPT Version :9

• Sequence 1: NP_001261559.1
• Gene: Arp3 / 38898
• FlyBaseID: FBgn0262716
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_001005386.1
• Gene: ACTR2 / 10097
• HGNCID: 169
• Length: 399
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 141/422 - (33%)
• Similarity: 213/422 - (50%)
• Gaps: 70/422 - (16%)

  Fly     9 VIDVGTGYSKLGFAGNKEPQFIIPSAIA---IKESARVGDTNTRRITKGIEDLDFFIGDEAFDAT 70
            |.|.|||:.|.|:||:..|:.|.|:.:.   |:.:.:||:...:...|    :|..:||||.:..
Human    10 VCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKNNKK----MDLMVGDEASELR 70

  Fly    71 G-YSIKYPVRHGLVEDWDLMERFLEQCVF--KYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFE 132
            . ..:.||:.:|:|.:||.| :.|....|  :.|..:..:...||||||:|..:|||...|:|||
Human    71 SMLEVNYPMENGIVRNWDDM-KHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFE 134

  Fly   133 TFNVPGLYIAVQAVLALAASWASRSAEERTLTGIVVDSGDGVTHVIPVAEGYVIGSCIKHIPIAG 197
            |:...|:|:|:||||.|.|        :..|||:||||||||||:.||.||:.:....:.:.|||
Human   135 TYQFSGVYVAIQAVLTLYA--------QGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAG 191

  Fly   198 RNITSFIQSLLREREVGIPPEQSLETAKAIKEKHCYICPDIAKE----------FAKYDTEPGKW 252
            |:||.::..||..|..........||.:.||||.||:..:|.:|          ...|....|:.
Human   192 RDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRI 256

  Fly   253 IRNFSGVNTVTKAPFNVDVGYERFLGPEIFFHPEFSNPDFTIPLSEIVDNVIQNCPIDVRRPLYN 317
            |:                ||.|||..||..|.|...|.: .:.::|::.|.||...||.|...|.
Human   257 IK----------------VGGERFEAPEALFQPHLINVE-GVGVAELLFNTIQAADIDTRSEFYK 304

  Fly   318 NIVLSGGSTMFKDFGRRLQRDIKRSVDTRLRIS--ENLSEGRIK----PKPIDVQVITHHMQRYA 376
            :|||||||||:.....||:|::|:....|:...  |.||:.:|:    |:           :::.
Human   305 HIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPR-----------RKHM 358

  Fly   377 VWFGGSMLA----STPEFYQVCHTKAAYEEYG 404
            |:.||::||    ....|:.   |:..|:|.|
Human   359 VFLGGAVLADIMKDKDNFWM---TRQEYQEKG 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_001261559.1	PTZ00280	2..417	CDD:240343	141/422 (33%)
ACTR2	NP_001005386.1	ACTIN	6..393	CDD:214592	141/422 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820