Protein Alignment Nulp1 and Tcf25

DIOPT Version :10

• Sequence 1: NP_648174.3
• Gene: Nulp1 / 38897
• FlyBaseID: FBgn0027549
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_001387879.1
• Gene: Tcf25 / 292082
• RGDID: 1309054
• Length: 677
• Species: Rattus norvegicus
• Alignment Length: 769
• Identity: 268/769 - (34%)
• Similarity: 392/769 - (50%)
• Gaps: 162/769 - (21%)

  Fly     1 MSARMLKKLQGD---ADKLAPPP------DDEDCE---------------------------ELS 29
            ||.|.|::|:|:   .:.|.|..      ||:|.|                           ||.
  Rat     1 MSRRALRRLRGEQRGQEPLGPDALQFVLLDDDDAEEEGPKTGLGGRRPGGAGKEGVRVNNRFELI 65

  Fly    30 DNDELED-----------------SDMQRYRKSHLNPFDLLNQAGLSLSESEFKED-DNETEHPS 76
            :.::|||                 |...:.|..|.||              |.|:| |...:..|
  Rat    66 NIEDLEDDLVVNGERSDCTLPDSASSGNKGRAKHGNP--------------ENKQDGDAAAKAGS 116

  Fly    77 AALPNATASAAKKKKKKRKKKA---KSSGNHISSEDNERQDKYFEKVDPLLGKVYDAVPRQSAKQ 138
            :...||:....|||||::.||:   :||.|.:     |..|:..|:::...|..:...|..|::
  Rat   117 SEQSNASGKLRKKKKKQKNKKSCTGESSENGL-----EDIDRILERIEDSSGFSHPGPPPLSSR- 175

  Fly   139 LVSAATGTTATKKLLAVELRHLNPQNEMRRTFGKRVVKVETK-RGRQKPTLKSTYMVTAKDSWPA 202
                       |.:|.||.|||||..|::|.||.|.|..|.: |.||:...|.|::.|.|.:||.
  Rat   176 -----------KHVLYVEHRHLNPDTELKRYFGARAVLGEQRPRQRQRVYPKCTWLTTPKSTWPR 229

  Fly   203 LTKNTITMKLLPAPDSPSVSSKSITDNGADVQWFAFEHSQYYQGVQQMFLSALERIDSEFLITLI 267
            .:|..::|:||.       |.|.::       :||||||:.||..|..||.|:|.::...::.|:
  Rat   230 YSKPGLSMRLLE-------SKKGLS-------FFAFEHSEEYQQAQHKFLVAVESMEPNNIVALL 280

  Fly   268 KRCPYHVDSLVQLSEVCKMTEDFSLASELLERALLLLESSLHINFSLTSGNCRLDYRRQENRSFY 332
            :..|||||||:|||:.|:..||..:|.:|:||||..:|...|..||||||.|||||||.||||||
  Rat   281 QTSPYHVDSLLQLSDACRFQEDQEMARDLIERALYSMECVFHPLFSLTSGTCRLDYRRPENRSFY 345

  Fly   333 IVLFKHAQYLEERACSRTAFEISKLLLSLQPDTDPLAMILVIDYYALRSKQFEWLVEFYEKYNAA 397
            :.|:|...:||:|.|.|||.|..||:|||:||.|||.|:|:||:.|||::.:|:|:..::::.|.
  Rat   346 LALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHMALRARNYEYLIRLFQEWEAH 410

  Fly   398 RNLNQLPNMAYSYALAL-----------HTLYGACERSNQALQYALLMFPGVLRPLLDEMSVQTD 451
            |||:||||.|:|..||.           |.|..|.::::..:|.||.||||||.|||:..||:.|
  Rat   411 RNLSQLPNFAFSVPLAYFLLSQQTDLPDHELSSARQQASLLIQQALTMFPGVLMPLLEYCSVRPD 475

  Fly   452 KRVLASSYFFADVSGNQSPALHQLVCLYVCRARVVWRQNEVLPWLESNVNIVLDRIESKDPLVNE 516
            ..|....:|..|...:|.|||.|||.||:.|:..:|::..::.|||.||:.||:.::|.||.|..
  Rat   476 ATVSNHRFFGPDAEISQPPALSQLVSLYLGRSHFLWKEPAIMSWLEENVHEVLEAVDSGDPAVEA 540

  Fly   517 YKEKRSLRYSGTPPRPILRHVILSDYKEKVPLAVFVSKEKQAIMTYDPLPPPNSVNCYHRKSSSS 581
            .:.:|.:.|. ..||.|.||||||:.||.| .|:......|::|.:|||||.:::..|.|  ...
  Rat   541 CENRRKVLYQ-RAPRNIHRHVILSEIKEAV-AALPSDVTTQSVMGFDPLPPVDTIYSYVR--PER 601

  Fly   582 SSPTTNTNNSVSMFFQSLLPSFNINNLAANAQLQEGAAPAAGAGAAAGDANIEVGIEQGAAGVAG 646
            .||.:: .|::::||:||||::.          .||..                 :|:|.||  |
  Rat   602 LSPVSH-GNTIALFFRSLLPNYT----------TEGER-----------------LEEGVAG--G 636

  Fly   647 EGEEAGLQQSLTLMMDAMRDFLQNFRIAEHLRSPETAAAQSTSSNDEEEGSSDY 700
            .....||.:    :|.|:||.:.||...: |..|.         .|..||..|:
  Rat   637 PNRNQGLNR----LMLAVRDMMANFHFND-LEVPR---------EDNPEGEGDW 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nulp1	NP_648174.3	Tcf25	236..567	CDD:461476	158/341 (46%)
Tcf25	NP_001387879.1	Tcf25	249..589	CDD:461476	158/341 (46%)