Protein Alignment Nulp1 and Nulp1

DIOPT Version :10

• Sequence 1: NP_648174.3
• Gene: Nulp1 / 38897
• FlyBaseID: FBgn0027549
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_061499270.1
• Gene: Nulp1 / 1276228
• VectorBaseID: AGAMI1_012399
• Length: 777
• Species: Anopheles gambiae
• Alignment Length: 799
• Identity: 358/799 - (44%)
• Similarity: 473/799 - (59%)
• Gaps: 121/799 - (15%)

  Fly     1 MSARMLKKLQGDADKLAPPPDDEDCEELSDNDELE---DSDMQRYRKS-----HLNPFDLLNQAG 57
            ||.|:|:||||:..::     .|..:|:||..:.:   :|...:.|.:     ::|.:|||||.
Mosquito     1 MSYRILRKLQGNELEI-----KEQIDEVSDGGDADYDTNSTSSQNRNNSKKQLNINRYDLLNQQ- 59

  Fly    58 LSLSESEFKEDDN-ETEHPSAALPNAT--ASAAKKKKKKRKKKAK--SSGNHISSEDNERQDKYF 117
            .||||||.||||| |||..:|..|.:.  |.|.|:||||:||..|  ||....|||||...:..|
Mosquito    60 QSLSESEVKEDDNDETEKDAADGPVSVHLAEAKKRKKKKKKKTGKYISSSARRSSEDNADIEDDF 124

  Fly   118 EKVDPLLGKVYDAVPRQSAK---------------------------QLVSAATGTTATKKLLAV 155
            .:....:.|::...||.|..                           :..:...|....|.||.|
Mosquito   125 TRTVKEVDKLFGNFPRDSTADHPHHHHHHHPPHHHHHHQDGGGGGPGEGKAGGAGAVTAKSLLNV 189

  Fly   156 ELRHLNPQNEMRRTFGKRVV-----KVETKRGRQKPTLKSTYMVTAKDSWPALTKNTITMKLLPA 215
            :.::||||.||:|.||.:||     |....||..: ..||||:|..|:|||.:.|:.|.|.|:.|
Mosquito   190 QHKNLNPQYEMKRMFGSKVVGDQQNKRRNARGASR-LQKSTYLVNPKESWPPVGKSGIYMNLVQA 253

  Fly   216 PDSPSVSS-----KSITDNGADVQWFAFEHSQYYQGVQQMFLSALERIDSEFLITLIKRCPYHVD 275
            |: |..|:     |:|.|.  :|.:||||||..|:.|||.||.|:|.:|||.:|.:|.:.|||||
Mosquito   254 PE-PGTSTSAAGPKAIFDK--NVIYFAFEHSPSYRQVQQKFLDAVESMDSENIIRIINQYPYHVD 315

  Fly   276 SLVQLSEVCKMTEDFSLASELLERALLLLESSLHINFSLTSGNCRLDYRRQENRSFYIVLFKHAQ 340
            ||:||||:||||:|.::||||:|.|||.||||.|..||||.|||||||||||||:.:|.||||.|
Mosquito   316 SLIQLSELCKMTDDHAMASELIEHALLALESSFHTMFSLTQGNCRLDYRRQENRALFIALFKHGQ 380

  Fly   341 YLEERACSRTAFEISKLLLSLQPDTDPLAMILVIDYYALRSKQFEWLVEFYEKYNAARNLNQLPN 405
            :||.|||||||.|::||:||..|..|||||||::||||:|:||:||||..||:::|..||:||||
Mosquito   381 HLESRACSRTALEVAKLILSFDPVNDPLAMILIVDYYAIRAKQYEWLVTLYEEWDATNNLSQLPN 445

  Fly   406 MAYSYALALHTLYGACERSNQALQYALLMFPGVLRPLLDEMSVQTDKRVLASSYFFADVSGNQSP 470
            ||||||:||..| ...|.:::||||||||||||||||:||:|:|.|.||...:||..........
Mosquito   446 MAYSYAMALFHL-KRTEAADKALQYALLMFPGVLRPLMDELSIQADSRVAGHNYFGPGAYNKALV 509

  Fly   471 ALHQLVCLYVCRARVVWRQNEVLPWLESNVNIVLDRIESKDPLVNEYKEKRSLRYSGTPPRPILR 535
            ||.||:.|||||:::|||..|:|||||.|||.||||:::|:.:|.||..|||.||| .|||.:||
Mosquito   510 ALQQLMSLYVCRSKLVWRDAELLPWLERNVNAVLDRVDAKEDVVAEYATKRSQRYS-NPPRQVLR 573

  Fly   536 HVILSDYKEKVPLAVFVSKEKQAIMTYDPLPPPNSVN-----------CYHRKSSSS-------- 581
            |::|||:|||||||.|:.||...::.||||||.:|:|           ||:....:.
Mosquito   574 HIVLSDFKEKVPLAQFIKKETDPMLMYDPLPPLDSINIYSRFVRKGLLCYYSTEDTQIRSFCPFC 638

  Fly   582 -SSPTTNT------NNSVSMFFQSLLPSFNINNLAANAQLQEGAAPAAGAGAAA------GDANI 633
             |.||..|      |:.:.:|||||||:|       |||.|..|.|||.|.|||      ..||:
Mosquito   639 FSRPTLTTNAQRLPNDPLHLFFQSLLPNF-------NAQAQPAAPPAAAAAAAAVAAAPPQQANV 696

  Fly   634 EVGIE------------QGAAGVAG----EGEEAGLQQSLTLMMDAMRDFLQNFRIAEHLRSPET 682
            .....            :||.|.||    .|..|....:|..:::|||:||...|..|.....:.
Mosquito   697 AAAAAAAAAAAAAAAGGEGAGGAAGADRDNGSMATYSSTLVTIVEAMREFLSGIRALERPNDADV 761

  Fly   683 AAAQSTSSNDEEEGSSDYI 701
            ..|:||    ||:..:|::
Mosquito   762 DEAEST----EEDEPNDFL 776

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nulp1	NP_648174.3	Tcf25	236..567	CDD:461476	206/330 (62%)
Nulp1	XP_061499270.1	None