Protein Alignment Sarm and sarm1

DIOPT Version :9

• Sequence 1: NP_001246662.1
• Gene: Sarm / 38895
• FlyBaseID: FBgn0262579
• Length: 1730
• Species: Drosophila melanogaster
• Sequence 2: XP_002937189.2
• Gene: sarm1 / 779619
• XenbaseID: XB-GENE-6033913
• Length: 719
• Species: Xenopus tropicalis
• Alignment Length: 633
• Identity: 297/633 - (46%)
• Similarity: 414/633 - (65%)
• Gaps: 17/633 - (2%)

  Fly   718 LEKINEVIRRAWAVPTHGHELGYSLCNSLRQSGGLDLLMK--NCVKPDLQFSSAQLLEQCLTTEN 780
            :.:|.:::..||.:|..|.|:...||.:||..|.||.|:.  ...:..:::.:.|||||.|..:|
 Frog    87 IAEIFQMVEEAWVMPAVGREVAQGLCETLRLEGALDRLLSLLQSSEASVKYQACQLLEQVLVADN 151

  Fly   781 RKHVVDNGLDKVVNVACVCTKN-SNMEHSRVGTGILEHLFKHSEGTCSDVIRLGGLDAVLFECRT 844
            |..:...||..|:|:    ||. .:...:|...|||||:|||||.|||.::..|||:.:||.||.
 Frog   152 RDRIARIGLGVVLNL----TKELGDPRLARSLCGILEHMFKHSEETCSQLVCNGGLEYILFWCRW 212

  Fly   845 SDLETLRHCASALANLSLYGGAENQEEMILRKVPMWLFPLAF-HNDDNIKYYACLAIAVLVANKE 908
            :|...|||||.||||.::|||..||..||.::...||||||| ..||.|:::|||||.||..|||
 Frog   213 TDPVVLRHCAVALANCAMYGGPCNQHLMIDKRAAEWLFPLAFSKEDDLIRFHACLAITVLATNKE 277

  Fly   909 IEAEVLKSGCLDLVEPFVTSHDPSAFARSNL---AHAHGQSKHWLKRLVPVLSSNREEARNLAAF 970
            ||.:|.:||.|.|||||::|.||..||||.|   .:..|::...|:||||:|.|:|.||:.:|||
 Frog   278 IEKDVERSGTLALVEPFISSLDPKEFARSLLDSSDNTQGRTGDDLQRLVPLLDSSRLEAQCIAAF 342

  Fly   971 HFCMEAGIKREQGNTDIFREINAIEALKN-VASCPNAIASKFAAQALRLIGETVPHKLSQQVPLW 1034
            :.|:|..||.:|.|..:|.||.|.::|:. |..|.:...|..|.:||:::||.||.::::.||.|
 Frog   343 YLCVEVAIKCQQKNIKLFNEIGATQSLRRIVCYCADGTVSSLAKRALQMMGEEVPRRIARSVPNW 407

  Fly  1035 SVEDVQEWVKQIGFNDYIDKFNESQVDGDLLLKLNQDNLRADIGIGNGILLKRFERELQNLKRMA 1099
            ...:||.|::||||::|.:.|.|:|:||||||:|....||.|:.:.:.|..|||.|||..||..|
 Frog   408 KPLEVQHWLQQIGFSNYSENFLENQIDGDLLLRLTMSELRDDLNMTSSITRKRFMRELVELKTFA 472

  Fly  1100 DYSSKDTAKMHQFLSEIGTDYCTYTYAMLNAGIDKCALPHVNEDMLMTECGIHNSIHRLRILNAV 1164
            :||:.|.:.:..:|..:...:..|||.::.||||:..|.||.|..|..:|.|....||:.||:|.
 Frog   473 NYSTCDRSNLADWLGSVDPRFRQYTYNLVTAGIDRNFLHHVTEQQLEEDCHISIGFHRVCILSAA 537

  Fly  1165 KN-LENSLPSSSEENMAKTLDVFVSYRRSNGSQLASLLKVHLQLRGFSVFIDVERLEAGKFDNGL 1228
            :. |.:.||.|..::.|...|||:|||||.||||||||||||.||||:.|||||:||||||::.|
 Frog   538 REMLHSPLPCSVGKSSADGPDVFISYRRSTGSQLASLLKVHLYLRGFTAFIDVEKLEAGKFEDKL 602

  Fly  1229 LNSIRQAKNFVLVLTPDALHRCINDEDCKDWVHREIVAALNSNCNIIPIIDQQFDWPEVERLPED 1293
            |:|:..|:||||:|:..||.:|:.|.|||||||:|||.|||::.||||:.| .|:||:...||||
 Frog   603 LHSVISARNFVLILSAKALDKCMGDNDCKDWVHKEIVTALNNSKNIIPVTD-HFEWPDPMTLPED 666

  Fly  1294 MRSVAHFNGVNWIHDYQDACIDKLERFLRGEKNIDRIAA---MVPGTP 1338
            ||:|..|||:.|.|:||||.::|:.|||:|..:.|..|.   .:.|||
 Frog   667 MRAVLKFNGIKWSHEYQDATVEKIIRFLQGRSSRDSSAGSEISLDGTP 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sarm	NP_001246662.1	SAM_SARM1-like_repeat1	1031..1099	CDD:188900	33/67 (49%)
		SAM	1031..1096	CDD:197735	31/64 (48%)
		SAM_SARM1-like_repeat2	1100..1169	CDD:188901	24/69 (35%)
		SAM	1111..1170	CDD:197735	21/59 (36%)
		TIR_2	1185..1285	CDD:290400	66/99 (67%)
sarm1	XP_002937189.2	SAM_SARM1-like_repeat1	404..472	CDD:188900	33/67 (49%)
		SAM_SARM1-like_repeat2	473..542	CDD:188901	23/68 (34%)
		TIR	557..697	CDD:214587	89/140 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	159	1.000	Domainoid score	I4051
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9015
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D113262at33208
OrthoFinder	1	1.000	-	-		FOG0007036
OrthoInspector	1	1.000	-	-		oto102586
Panther	1	1.100	-	-	LDO	PTHR22998
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5128
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.020