Protein Alignment CG7565 and KIAA0319L

DIOPT Version :10

• Sequence 1: NP_648171.1
• Gene: CG7565 / 38893
• FlyBaseID: FBgn0035833
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: XP_016857855.1
• Gene: KIAA0319L / 79932
• HGNCID: 30071
• Length: 1054
• Species: Homo sapiens
• Alignment Length: 1019
• Identity: 351/1019 - (34%)
• Similarity: 519/1019 - (50%)
• Gaps: 120/1019 - (11%)

  Fly    95 EAYLW---------NCLQACCEKPRNGSSACNVVLVFKAKCYHIRCQSNEACLPKLRVRMPNEKV 150
            |.:||         :|..|||:     .|||:|....:..|....|...::| ...|....|.
Human    70 ENHLWLLEGTPSLQSCWAACCQ-----DSACHVFWWLEGMCIQADCSRPQSC-RAFRTHSSNS-- 126

  Fly   151 QMVLVNPLGDATWPQLLKAEAAKQNAEILPYDEA------ALNF--WKQ--PR-----------R 194
              :||          .||......:...||.|:.      ..|:  |:|  ||           :
Human   127 --MLV----------FLKKFQTADDLGFLPEDDVPHLLGLGWNWASWRQSPPRAALRPAVSSSDQ 179

  Fly   195 LSYLARNQETPVYEDEDFPLADK--RMNQMIFQPDENDVLANEELGYYDSNAKFT-----TCDME 252
            .|.:.:.|:.....|...|:..:  ::|      |.|::......|..:.:...|     |.|:.
Human   180 QSLIRKLQKRGSPSDVVTPIVTQHSKVN------DSNELGGLTTSGSAEVHKAITISSPLTTDLT 238

  Fly   253 TPCPPPQQCVPLQPNAVRGVCTCPEGFVWNKQRKCVMA----AVPYSSYLTSNEAGQQEAAASEN 313
            .......:.|.:||....|:.|.|.........|..:|    ..|..||.|..      ..||..
Human   239 AELSGGPKNVSVQPEISEGLATTPSTQQVKSSEKTQIAVPQPVAPSYSYATPT------PQASFQ 297

  Fly   314 SPEVSTPPLKAEQNKDIVVSV-MSKEVRLPEQEVTLAAFTVPDEQTSDTKYKYLWTLISQPKGPM 377
            |.....|.:     |::|||. .|.::.||:.||.|.|:.:.:....:| |.|.|.||:.|: ..
Human   298 STSAPYPVI-----KELVVSAGESVQITLPKNEVQLNAYVLQEPPKGET-YTYDWQLITHPR-DY 355

  Fly   378 NGTISDQSKSKVKLSNLSEGLYTFKVTVTGDNGTFGEATANVTVLPENRINQPPQVIISPREQII 442
            :|.:..:....:|||.|:.|||.|||.|.|.| ..||...||||.||.|.|:||..|:||:.|.|
Human   356 SGEMEGKHSQILKLSKLTPGLYEFKVIVEGQN-AHGEGYVNVTVKPEPRKNRPPIAIVSPQFQEI 419

  Fly   443 RQPTTNAILDGSTSTDDDKITNWHWEVISGPIGYQPVLPEVNTLQLDLTSPGNYTFKLTVTDSNN 507
            ..|||:.::|||.|||||||..:|||.:.||:..:.:..:...|:|....||||||.|||.||:.
Human   420 SLPTTSTVIDGSQSTDDDKIVQYHWEELKGPLREEKISEDTAILKLSKLVPGNYTFSLTVVDSDG 484

  Fly   508 VTNSTTATIAVLKETDYAPVANAGDAVILYLPNNNVTLNGTASSDDHEIVAWEWTKDASDEAKAV 572
            .||||||.:.|.|..||.||||||...::.||.|::||.|..|:|||.|.::||:...|.:.|.|
Human   485 ATNSTTANLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPSSKGKVV 549

  Fly   573 DMQNTRTPYVQLSNLEEGMYTFVLKVTDGSGQSSTAKVHVFVKPPTNSPPVAEAGSNTTTSLPIN 637
            :||..|||.:|||.::||.||:.|.|||..||.:||:|.|.|:|..|.||.|:||.:...:||::
Human   550 EMQGVRTPTLQLSAMQEGDYTYQLTVTDTIGQQATAQVTVIVQPENNKPPQADAGPDKELTLPVD 614

  Fly   638 WVLLNGSDSKDDIGIKSYLWKQ-----LSGPNNAVILKSNSSIANATSLTLGLYEFELTVADENN 697
            ...|:||.|.||..|.||||::     ..||:...:..:|||:|..|.|.:|.|.|.|||.||.|
Human   615 STTLDGSKSSDDQKIISYLWEKTHFFFCRGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERN 679

  Fly   698 NTATDTTWVKIVQERNAAPIANAGGDHTVTLPATAIYFNGSKSWDDLAVVKYLWTRDEHSLAAGV 762
            ..:..:..|.:.:|.|..|||...|:..:|||.:....:||||.||..:|.|||||||.|.|||.
Human   680 LQSQSSVNVIVKEEINKPPIAKITGNVVITLPTSTAELDGSKSSDDKGIVSYLWTRDEGSPAAGE 744

  Fly   763 IVADTDKEPVMILTNLVQGRYVFTLTVSDDQGLTSSDTVSVNVRRDPKLLNLVQMTLPMGISVLV 827
            ::..:|..|::.|:|||:|.|.|.|.|:|.:|.:.:|..:|.|:.||:..|||::.|.:.:|.|.
Human   745 VLNHSDHHPILFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKPDPRKNNLVEIILDINVSQLT 809

  Fly   828 QSELDSVVQKLQLLLGD-ENKIQVRELKYDLHTD-ATVLVFYV-NDGQGKALDGLQVERQLRTQL 889
            :......::::.:|||. ::.|.|:  |...:|: :|.:||:| |:...:...|.:|...|:::|
Human   810 ERLKGMFIRQIGVLLGVLDSDIIVQ--KIQPYTEQSTKMVFFVQNEPPHQIFKGHEVAAMLKSEL 872

  Fly   890 QKD-ASILGAFAVDIRTSVCQSDCSGHGSCNPITRACICEAFWMPSAGYFFNNQ----EANCDWS 949
            :|. |..|...|:::.|..||.:||.||.|:..|:.|||:.|||.:   |...|    ::||:||
Human   873 RKQKADFLIFRALEVNTVTCQLNCSDHGHCDSFTKRCICDPFWMEN---FIKVQLRDGDSNCEWS 934

  Fly   950 ILYVFVGVIVGCLLLSGVFWGIACAC-RQSKKPRLRQKVQKYSLIGNKDEEAANY---SR----- 1005
            :|||.:...|..:.|..:.|.:.|.| ||..||:   :..||.::...|:|:...   ||
Human   935 VLYVIIATFVIVVALGILSWTVICCCKRQKGKPK---RKSKYKILDATDQESLELKPTSRAGIKQ 996

  Fly  1006 -----NTSL--TESETDS-DVLFETRTKSNGLGKHKSHNSHSHG 1041
                 ::||  :|||.|| |.:|....:..|...|..:.|..:|
Human   997 KGLLLSSSLMHSESELDSDDAIFTWPDREKGKLLHGQNGSVPNG 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7565	NP_648171.1	MANEC	52..153	CDD:471454	16/66 (24%)
		myxo_dep_M36	<428..810	CDD:468355	176/386 (46%)
KIAA0319L	XP_016857855.1	myxo_dep_M36	<405..792	CDD:468355	176/386 (46%)