DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7565 and spint1b

DIOPT Version :9

Sequence 1:	NP_648171.1	Gene:	CG7565 / 38893	FlyBaseID:	FBgn0035833	Length:	1069	Species:	Drosophila melanogaster
Sequence 2:	NP_001104693.1	Gene:	spint1b / 797346	ZFINID:	ZDB-GENE-071218-1	Length:	499	Species:	Danio rerio

Alignment Length:	191	Identity:	57/191 - (29%)
Similarity:	83/191 - (43%)	Gaps:	46/191 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   523 DYAPVANAGDAVILYLPNNNVTLNGTASSDDHEIVAWEWTKDASDEAKAVDMQNTR-TPYVQLSN 586
            |..|:||||..|::. ||.:|.|||..|.||.|||.:||:....:  |:|.|:.|. ...:::||
Zfish   136 DSPPIANAGRDVVVQ-PNEDVLLNGNESWDDKEIVNYEWSLTRGN--KSVHMEKTNFRDQIRVSN 197

  Fly   587 LEEGMYTFVLKVTDGSGQSSTAKVHVFVKPPTNSPPVAEAGSNTTTSLPINWVLLNGSDSKDDIG 651
            |..|:|.|.|.|||.:.||.:|:|.|.|                          |....|:
Zfish   198 LIPGVYEFKLTVTDSADQSDSAQVIVLV--------------------------LTSEQSE---- 232

  Fly   652 IKSYLWKQLSGPNNAVILKSNSSIANATSLTLGLYEFELTVADENN--------NTATDTT 704
             :..|..:.:||..|..::.|   .||.|.....:.|...:.:.||        |...:||
Zfish   233 -RHCLTPKKTGPCRASFIRWN---YNAASRRCEQFIFGGCMENSNNYLSETECQNACENTT 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7565	NP_648171.1	MANEC	52..153	CDD:297649
		PKD	<454..518	CDD:214510
		PKD	527..615	CDD:214510	38/88 (43%)
		PKD	716..805	CDD:238084
spint1b	NP_001104693.1	MANEC	31..116	CDD:284837
		PKD	148..225	CDD:214510	33/79 (42%)
		Kunitz_BPTI	235..285	CDD:278443	12/52 (23%)
		LDLa	308..342	CDD:238060
		Kunitz_BPTI	363..413	CDD:278443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575830
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930