DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7565 and lrp11

DIOPT Version :9

Sequence 1:	NP_648171.1	Gene:	CG7565 / 38893	FlyBaseID:	FBgn0035833	Length:	1069	Species:	Drosophila melanogaster
Sequence 2:	XP_005160377.1	Gene:	lrp11 / 569216	ZFINID:	ZDB-GENE-030131-7847	Length:	544	Species:	Danio rerio

Alignment Length:	290	Identity:	72/290 - (24%)
Similarity:	116/290 - (40%)	Gaps:	46/290 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   366 LWTLISQPKGPMNGTISDQSKSKVKLSNLSEGLYTFKVTV------------TGDNGTFGEATAN 418
            ||  :|...|..:   |..|:.|.::|.:.|.|..|:..:            .||....|...|.
Zfish    15 LW--VSSSAGARS---SPTSELKSRISGVEELLEEFRKQLQQDEPSSREQEGDGDRCVAGFRAAE 74

  Fly   419 VTVLPENR--------INQPPQVII---SPREQIIRQPTTNAILDGSTSTDDDKITNWHW----- 467
            ..::..:.        ::.||:|..   ..|........|.||:.......||.:..:.:
Zfish    75 SRIIRASASIEQGAAFLSAPPRVFSWRDCARACCSLPHCTVAIIQEDLKQPDDSLRCYLFNCTYR 139

  Fly   468 --EVISGPIGYQPVLPEVNTLQLDLTSPGNYTFKLTVTD--SNNVTNSTTATIAVLKETDYAPVA 528
              .|.|  ..|||.....:.|.....:||.     ..||  :.....:.....|::::.|..|.:
Zfish   140 GKSVCS--FSYQPGFSTYSRLNDSSGAPGT-----AATDRPAGRPAPALGEEEAMMQDLDEPPRS 197

  Fly   529 NAGDAVILYLPNNNVTLNGTASSDDHEIVAWEWTKDASDEAKAVDMQNTRTPYVQLSNLEEGMYT 593
            :||..:::.||.:...|:|..|:|||.|..:||.....|  .:|.|:.|....::||.|.||:||
Zfish   198 DAGQDLVVQLPTDWAVLDGRDSTDDHHITRYEWALVRGD--PSVKMKVTHPGLLKLSGLREGVYT 260

  Fly   594 FVLKVTDGSGQSSTAKVHVFVKPPTNSPPV 623
            |.:.|.|.:||.|:..|.|.|..|..:..|
Zfish   261 FEITVIDTAGQKSSDNVSVSVLAPAPNAQV 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7565	NP_648171.1	MANEC	52..153	CDD:297649
		PKD	<454..518	CDD:214510	12/72 (17%)
		PKD	527..615	CDD:214510	32/87 (37%)
		PKD	716..805	CDD:238084
lrp11	XP_005160377.1	LolA	12..>64	CDD:302782	11/53 (21%)
		MANEC	66..154	CDD:284837	16/89 (18%)
		LDLa	295..329	CDD:238060
		KU	379..432	CDD:238057
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575821
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930