DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7565 and Spint1

DIOPT Version :9

Sequence 1:	NP_648171.1	Gene:	CG7565 / 38893	FlyBaseID:	FBgn0035833	Length:	1069	Species:	Drosophila melanogaster
Sequence 2:	NP_001004265.2	Gene:	Spint1 / 311331	RGDID:	1303138	Length:	507	Species:	Rattus norvegicus

Alignment Length:	237	Identity:	47/237 - (19%)
Similarity:	75/237 - (31%)	Gaps:	73/237 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 DMETPCPPPQQC----VPLQPNAVRGV--------CTCPEGFVWNKQRKCVMAAVP-YSSYLTSN 301
            |....|...|.|    |.|||:.....        |...:.||      |..|... :.:|||.:
  Rat    80 DCVRACCTTQNCNLALVELQPDGGEDAISACFLMNCLYEQNFV------CKFAPKDGFINYLTQD 138

  Fly   302 EAGQQEAAASENSPEVSTP------PLKAEQNKDIVVSVMSKEVRLPEQEVTLAAFTVPDEQTSD 360
            .........:........|      .||.:..|.:|:.                     |...:|
  Rat   139 LYNSYRELRTRGFGGSRIPRIWMGIDLKVQLQKPLVLR---------------------DADNTD 182

  Fly   361 TKYKYLWTLISQPKGPMNGTISDQSKSKVKLSNLSEGLYTFKVTVTGDNGTFGEATANVTV---- 421
                  |.|:   :|..:.::......:|:|..|.||.|.|::|.|..:..  |.|.|:|:
  Rat   183 ------WHLL---QGDQDVSVKRNHPEEVELWGLKEGTYLFQLTRTDSDQL--EETVNLTITVLT 236

  Fly   422 --------LPENRINQP----PQVIISPREQIIRQPTTNAIL 451
                    |...::.:.    |:....|:|||.:..|....|
  Rat   237 AEQTEDYCLASYKVGRCRGSFPRWYYDPKEQICKSFTFGGCL 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7565	NP_648171.1	MANEC	52..153	CDD:297649
		PKD	<454..518	CDD:214510
		PKD	527..615	CDD:214510
		PKD	716..805	CDD:238084
Spint1	NP_001004265.2	MANEC	44..133	CDD:284837	13/58 (22%)
		Kunitz_BPTI	243..295	CDD:278443	8/36 (22%)
		LDLa	313..344	CDD:197566
		Kunitz_BPTI	368..420	CDD:278443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336668
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930