DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7565 and T21D12.7

DIOPT Version :9

Sequence 1:	NP_648171.1	Gene:	CG7565 / 38893	FlyBaseID:	FBgn0035833	Length:	1069	Species:	Drosophila melanogaster
Sequence 2:	NP_001343686.1	Gene:	T21D12.7 / 24104914	WormBaseID:	WBGene00020648	Length:	661	Species:	Caenorhabditis elegans

Alignment Length:	168	Identity:	34/168 - (20%)
Similarity:	65/168 - (38%)	Gaps:	38/168 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   810 KLLNLVQMTLPMGISV--LVQSELDSVVQKLQLLLGDENKIQVRELKYDLHTDATVLVFYVNDGQ 872
            |...:.|:.|.:|::|  |..:||...|.:|...:|....:......|...::....:.::.:|.
Worm     4 KTSTIFQILLLLGVTVIHLDGNELGGFVCRLPKNVGFACGVTTPHSAYYFDSEIRECIEFMFEGC 68

  Fly   873 G----------KALDGLQVERQLRTQLQKDASILGAFAVDIRTSVCQSD---CSGHGSC--NPIT 922
            |          :.::|.    :..||..|...::. ||.:|:.  |..:   |.|...|  |.::
Worm    69 GGNQNRFSSRQECINGC----KSLTQCGKGMPLMD-FAGNIKR--CDGERVPCPGSHECVGNGMS 126

  Fly   923 RAC------ICEAF--------WMPSAGYFFNNQEANC 946
            ..|      ||:|.        ..|:..|:|::....|
Worm   127 SVCCQKAGRICQASVHPGTPCGVPPATRYYFDSSSKTC 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7565	NP_648171.1	MANEC	52..153	CDD:297649
		PKD	<454..518	CDD:214510
		PKD	527..615	CDD:214510
		PKD	716..805	CDD:238084
T21D12.7	NP_001343686.1	Kunitz_BPTI	31..86	CDD:278443	7/58 (12%)
		Lustrin_cystein	91..131	CDD:317074	10/42 (24%)
		Kunitz_BPTI	136..189	CDD:278443	7/29 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157441
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930