DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7565 and Tfpi

DIOPT Version :9

Sequence 1:	NP_648171.1	Gene:	CG7565 / 38893	FlyBaseID:	FBgn0035833	Length:	1069	Species:	Drosophila melanogaster
Sequence 2:	NP_001342200.1	Gene:	Tfpi / 21788	MGIID:	1095418	Length:	306	Species:	Mus musculus

Alignment Length:	348	Identity:	64/348 - (18%)
Similarity:	100/348 - (28%)	Gaps:	117/348 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ICNLLLLATAMSSAYADVTTQNALLVGSKKHKET--------SPDNSVGGSISPNLVCHKMLRHV 64
            :|.||.|.....:|.::........:||.|...|        .|..::..|...|:..|:....:
Mouse    15 VCLLLSLVPEFLNALSEEADDTDSELGSMKPLHTFCAMKADDGPCKAMIRSYFFNMYTHQCEEFI 79

  Fly    65 FENATPRDEQQAGVFEE-------------YKPPPDAVEP----LEEE---------AYLWNCLQ 103
            : .....:|.:....||             .|....|..|    |||:         .||:|...
Mouse    80 Y-GGCEGNENRFDTLEECKKTCIPGYEKTAVKAASGAERPDFCFLEEDPGLCRGYMKRYLYNNQT 143

  Fly   104 ACCEKPRNGSSACNVVLVFKAKCYHIRCQSNEACLPKLRVRMPNEKVQMVLVNPLGDATWPQLLK 168
            ..||:...|....|      ...:....:..:.|...:....|..:|||      .|........
Mouse   144 KQCERFVYGGCLGN------RNNFETLDECKKICENPVHSPSPVNEVQM------SDYVTDGNTV 196

  Fly   169 AEAAKQNAEILPYDEAALNFWKQPRRLSYLARNQETPVYEDEDFPLADKRMNQMIFQPDENDVL- 232
            .:.:..|..::|...      |.|||..|..|                    ....||.::.:.
Mouse   197 TDRSTVNNIVVPQSP------KVPRRRDYRGR--------------------PWCLQPADSGLCK 235

  Fly   233 ANEELGYYDS----------------NAKFTTCDMETPCPPPQQCVPLQPNAVRGVCTCPEGFVW 281
            |:|...||:|                |..|||         .::|:.          :|..|.:.
Mouse   236 ASERRFYYNSATGKCHRFNYTGCGGNNNNFTT---------RRRCLR----------SCKTGLIK 281

  Fly   282 NK--------QRKCVMAAVPYSS 296
            ||        :||.....|.|.|
Mouse   282 NKSKGVVKIQRRKAPFVKVVYES 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7565	NP_648171.1	MANEC	52..153	CDD:297649	22/126 (17%)
		PKD	<454..518	CDD:214510
		PKD	527..615	CDD:214510
		PKD	716..805	CDD:238084
Tfpi	NP_001342200.1	KU	48..101	CDD:238057	8/53 (15%)
		Kunitz_BPTI	120..171	CDD:394972	10/56 (18%)
		Kunitz_BPTI	224..276	CDD:394972	12/70 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833093
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930