DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7565 and Wfikkn1

DIOPT Version :9

Sequence 1:	NP_648171.1	Gene:	CG7565 / 38893	FlyBaseID:	FBgn0035833	Length:	1069	Species:	Drosophila melanogaster
Sequence 2:	NP_001093924.1	Gene:	Wfikkn1 / 215001	MGIID:	2670967	Length:	552	Species:	Mus musculus

Alignment Length:	490	Identity:	97/490 - (19%)
Similarity:	150/490 - (30%)	Gaps:	180/490 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 FENATPRDEQQAGVFEEYKPPPDAVEPLEEEAYLWNCLQAC-----CEKPRNGSSACNVVLVFKA 124
            |.:..|...:.|...|.::.|...     .:..:|:....|     |||..:.:.|.: .|.:..
Mouse    83 FPSGGPAVPETAASCEGFQCPQQG-----SDCDIWDGQPVCRCRDRCEKEPSFTCASD-GLTYYN 141

  Fly   125 KCYHIRCQSNEACLPKLRVRM-------------PNEKVQMVLVNPLGDATWPQLLKAEAAKQNA 176
            :||    ...||||..|.:.:             |..........| |.|..|..|....:.|..
Mouse   142 RCY----MDAEACLRGLHLHVVPCKHILSWPPSSPGPPETTARPTP-GAAPMPPALYNSPSPQAV 201

  Fly   177 EI-----LPYDEAALNFWKQPRRLSYLARNQETPVYEDEDFPLADKRMNQ---MIFQPDE---ND 230
            .:     |..|.:.    :.|..:::                  :|:.:|   :|.:||:   |.
Mouse   202 HVGGTASLHCDVSG----RPPPAVTW------------------EKQSHQRENLIMRPDQMYGNV 244

  Fly   231 VLAN-----------EELGYYDSNA-----------------KFTTCDMETPCP-------PPQQ 260
            |:.:           |:.|.|...|                 :.||.|.:...|       ..|.
Mouse   245 VVTSIGQLVLYNAQLEDAGLYTCTARNAAGLLRADFPLSVLQRATTQDRDPGIPALAECQADTQA 309

  Fly   261 CV-PLQPNAV-------RGVC-TCP--------EGFVWNK--QRKCV-----MAAVP-------- 293
            || |..|:.|       ||.| |.|        .||...:  |:.||     :.|:|
Mouse   310 CVGPPTPHHVLWRFDPQRGSCMTFPALRCDGAARGFETYEACQQACVRGPGDVCALPAVQGPCQG 374

  Fly   294 ------YSSYL-------------TSNEAGQQEAAASENSPEVSTPPLKAEQNKD---------- 329
                  ||..|             .||....:| :..:..|...|||.:|.:.|.
Mouse   375 WEPRWAYSPLLQQCHPFVYSGCEGNSNNFETRE-SCEDACPVPRTPPCRACRLKSKLALSLCRSD 438

  Fly   330 -IVVSVMSKEVRLPEQEVTLAAFTVPDEQTSDTK--YKYLWTLISQPKGPMNGTISDQSKSKVKL 391
             .:|..:::.:..||....:|...: |:...|.|  .|:|.|                ...:|.|
Mouse   439 FAIVGRLTEVLEEPEAAGGIARVAL-DDVLKDDKMGLKFLGT----------------KYLEVTL 486

  Fly   392 SNLSEGLYTFKVT-VTGDNGTFGEATANVTVLPEN 425
            |.:........|| |.|.....||....|.||..|
Mouse   487 SGMDWACPCPNVTAVDGPLVIMGEVREGVAVLDAN 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7565	NP_648171.1	MANEC	52..153	CDD:297649	20/105 (19%)
		PKD	<454..518	CDD:214510
		PKD	527..615	CDD:214510
		PKD	716..805	CDD:238084
Wfikkn1	NP_001093924.1	WAP	34..80	CDD:278522
		KAZAL_FS	124..161	CDD:238052	12/41 (29%)
		I-set	196..284	CDD:254352	15/109 (14%)
		Ig_3	204..284	CDD:143242	14/101 (14%)
		KU	311..356	CDD:294074	12/44 (27%)
		KU	361..413	CDD:197529	8/52 (15%)
		NTR_like	431..541	CDD:295338	23/108 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833097
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930