Protein Alignment CG7565 and D130043K22Rik

DIOPT Version :10

• Sequence 1: NP_648171.1
• Gene: CG7565 / 38893
• FlyBaseID: FBgn0035833
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: NP_001074520.1
• Gene: D130043K22Rik / 210108
• MGIID: 3036268
• Length: 1081
• Species: Mus musculus
• Alignment Length: 1095
• Identity: 362/1095 - (33%)
• Similarity: 523/1095 - (47%)
• Gaps: 176/1095 - (16%)

  Fly    84 PPPDAVE--PLEEEAYLWNCLQACCEKPRNGSSACNVVLVFKAKCYHIRCQSNEACLPKLR---- 142
            |.|:.:.  .:.:...:.:|..|||:     ...|::...|:..||.::|..:|.|.|:..
Mouse    38 PNPETIRIMRVSQTFSVGDCTAACCD-----LLTCDLAWWFEGSCYLVKCMRSENCEPRTTGPIR 97

  Fly   143 -----VRMPNEKVQMVLVNPLGDATWPQLLKAEAAKQNAEILPYDEAALNFWKQPRRLSYLARN- 201
                 ||.|.::...:|  ..||....:...:.|...:.|.|..|            |.:|.::
Mouse    98 SYLTFVRRPVQRPGQLL--DYGDMMLSRGSPSGAWGDSLEDLRKD------------LPFLGKDG 148

  Fly   202 --QETPVYEDEDFPLADKRMNQMIFQPDEN------------DVLANEELGYYDSNAKFT----T 248
              :||..|.||     .|.:.:.:.||...            .:|.:.|.|:   ||..|    .
Mouse   149 GPEETTEYSDE-----YKDLERGLLQPSNQQDPRGSAEYPDWSLLPSNEGGF---NATATGDNSA 205

  Fly   249 CDME-----TPCPPPQQCVPLQPNAVRGVCTCPE------GFVWNKQRKCVMAAVPYSSYLTSNE 302
            ..||     ||.|..|:    |..|:......|.      ..||...    .:.:|....|...|
Mouse   206 ASMEKLQDPTPHPLDQE----QLQALNESTWSPTPGHSSISSVWPSS----ASPLPTEEGLEGEE 262

  Fly   303 AGQ-QEAAASENSPEVSTP------------PLKAEQNKDIVVSVMSKE---------------- 338
            ..| ||..::.:..||..|            |...|:|.:..|:..|::
Mouse   263 TLQLQEQPSNSSGKEVPMPSHNPSPASLESSPATTEKNSNFTVTPRSRKHSTPTFPTSTVLTGLT 327

  Fly   339 --------------------------VRLPEQEVTLAAFTVPDEQTSDTKYKYLWTLISQPKGPM 377
                                      :.||::|..|.| :|.....:||.|.|.|:|:|.|. ..
Mouse   328 PPPWPLSPTASRTVKALAVSAGDNLVLTLPDREAELKA-SVEPAPPADTTYSYEWSLMSHPV-DF 390

  Fly   378 NGTISDQSKSKVKLSNLSEGLYTFKVTVTGDNGTFGEATANVTVLPENRINQPPQVIISPREQII 442
            .|.|..::|..:.||.||.|||.|:|.|:.:| .|||...||||:|..|:||||..::||:.|.:
Mouse   391 QGKIKQENKPTLHLSQLSVGLYAFRVAVSSEN-AFGEGYVNVTVMPAARVNQPPVAVVSPQTQEL 454

  Fly   443 RQPTTNAILDGSTSTDDDKITNWHWEVISGPIGYQPVLPEVNTLQLDLTSPGNYTFKLTVTDSNN 507
            ..|.|:|::|||.||||.:|.::|||.:.||...:....:...|:|....||||||:||:|||:.
Mouse   455 SVPLTSALIDGSQSTDDTEIVSYHWEEVDGPFLGEEFPADTPILRLSNLVPGNYTFRLTITDSDG 519

  Fly   508 VTNSTTATIAVLKETDYAPVANAGDAVILYLPNNNVTLNGTASSDDHEIVAWEWTKDASDEAKAV 572
            .||||||::.:....||.||||||....:.||.|.:.|||..|||||:||.:||......|:|.:
Mouse   520 ATNSTTASLVIRDAVDYPPVANAGPNQTITLPQNTIILNGNQSSDDHQIVLYEWFAGPGGESKEM 584

  Fly   573 DMQNTRTPYVQLSNLEEGMYTFVLKVTDGSGQSSTAKVHVFVKPPTNSPPVAEAGSNTTTSLPIN 637
            .||..:|||:.||.|:||.|||.|.|||.|||.|||.|.|.|:...|..|||.||.:.....|:.
Mouse   585 VMQGAQTPYLHLSELQEGEYTFQLMVTDSSGQQSTALVAVTVQAENNQAPVAVAGPDKELVFPVQ 649

  Fly   638 WVLLNGSDSKDDIGIKSYLWKQLSGPNNAVILKSNSSIANATSLTLGLYEFELTVADENNNTATD 702
            ...|:||.|.||.||..|.|:.:.||:...:...:.:||..|.|.:|:|.|.|||.|:...::|.
Mouse   650 SATLDGSRSSDDHGIVCYHWEHIRGPSAVEMENVDKAIATVTGLQVGIYHFRLTVRDQQGLSSTS 714

  Fly   703 TTWVKIVQERNAAPIANAGGDHTVTLPATAIYFNGSKSWDDLAVVKYLWTRDEHSLAAGVIVADT 767
            |..|.:.:|.|:.|.|.|||.|.:.||..:|..:||:|.||..:|.|||.||..|.|||.::..:
Mouse   715 TLTVAVKKENNSPPRAQAGGRHVLILPNNSITLDGSRSTDDRGIVSYLWIRDGQSPAAGDVIGGS 779

  Fly   768 DKEPVMILTNLVQGRYVFTLTVSDDQGLTSSDTVSVNVRRDPKLLNLVQMTLPMGISVLVQSELD 832
            |....:.|||||:|.|.|.|.|:|.||.:.||..:|.|..|||...||::.|.:|:..|.:.:.:
Mouse   780 DHRAALQLTNLVEGVYTFHLLVTDSQGASDSDAATVEVLPDPKKDGLVELILQVGVEQLTEQQKE 844

  Fly   833 SVVQKLQLLLG--DENKIQVRELKYDLHTD-ATVLVFYVNDGQG-KALDGLQVERQLRTQLQKDA 893
            ::|::|.:||.  |.:   |:.||...||| :||:||||..|.. |.|....|.|.|..:|.|:.
Mouse   845 TLVRQLAVLLNVLDSD---VKVLKIQAHTDVSTVIVFYVQSGSPFKVLRAAAVARNLHKRLSKEK 906

  Fly   894 SILGAFAV-DIRTSVCQSDCSGHGSCNPITRACICEAFWMPS--AGYFFNNQEANCDWSILYVFV 955
            .....|.| .:.|:.|...|||||.|:|||:.|||...||.:  ..|.::. |:||:||:.||..
Mouse   907 EAFLLFKVLRVDTAGCLLKCSGHGHCDPITKRCICSQLWMENLIQRYMWDG-ESNCEWSVFYVAA 970

  Fly   956 GVIVGCLLLSGVFWGIACACRQSKKPRLRQKVQKYSLIGNKDEEAA----------------NYS 1004
            ..:...||...|.|...|.||:.|:.::|:|. ||:::.:.||:..                |.|
Mouse   971 LALTLTLLTGAVSWLCICCCRRRKRTKIRKKT-KYTILDSMDEQERMELRPKYGIKHRSTEHNSS 1034

  Fly  1005 RNTSLTESETDSDVLFETRTKSNGLGKHKSHNSHSHGHGSSGGSGSSGRDGHKYG 1059
            ...|.:|.|:|.|.||.......|:.|           ||..|   ..|:|..:|
Mouse  1035 LMVSESEFESDQDTLFSRERMERGVLK-----------GSLNG---CARNGVSFG 1075

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7565	NP_648171.1	MANEC	52..153	CDD:471454	17/79 (22%)
		myxo_dep_M36	<428..810	CDD:468355	171/381 (45%)
D130043K22Rik	NP_001074520.1	MANEC	23..102	CDD:471454	14/68 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	168..331		33/173 (19%)
		REJ	<284..571	CDD:366875	105/289 (36%)
		myxo_dep_M36	<440..825	CDD:468355	173/384 (45%)
		Endocytosis signal	1004..1007		1/2 (50%)