DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7565 and Ambp

DIOPT Version :9

Sequence 1:	NP_648171.1	Gene:	CG7565 / 38893	FlyBaseID:	FBgn0035833	Length:	1069	Species:	Drosophila melanogaster
Sequence 2:	NP_031469.1	Gene:	Ambp / 11699	MGIID:	88002	Length:	349	Species:	Mus musculus

Alignment Length:	219	Identity:	43/219 - (19%)
Similarity:	66/219 - (30%)	Gaps:	70/219 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   723 DHTVTLPATAIYFNGSKS-----WDDLAVVKYL-WTRDEHSLAAGVIVADTDKEPVMILTNLVQG 781
            |...|||...:..|.|:|     |.:|||.... |                       |:.:...
Mouse    20 DPASTLPDIQVQENFSESRIYGKWYNLAVGSTCPW-----------------------LSRIKDK 61

  Fly   782 RYVFTLTVSDDQGLTSSDTVSVNVRRDPKLLNLVQMTLPMGISVLVQSELDSVVQKLQL---LLG 843
            ..|.||.:.:....|.....|...||.                  |..|:....||..:   .|.
Mouse    62 MSVSTLVLQEGATETEISMTSTRWRRG------------------VCEEITGAYQKTDIDGKFLY 108

  Fly   844 DENKIQVRELKYDLHTDATVLVFYVNDGQGKALDGLQV-------ERQLRTQLQKDASILGAFAV 901
            .::|..:....|.:||:......::.. :.....||.:       |.|||..|.::..
Mouse   109 HKSKWNITLESYVVHTNYDEYAIFLTK-KSSHHHGLTITAKLYGREPQLRDSLLQEFK------- 165

  Fly   902 DIRTSVCQSDCS-----GHGSCNP 920
            |:..:|..|:.|     ..|.|.|
Mouse   166 DVALNVGISENSIIFMPDRGECVP 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7565	NP_648171.1	MANEC	52..153	CDD:297649
		PKD	<454..518	CDD:214510
		PKD	527..615	CDD:214510
		PKD	716..805	CDD:238084	18/87 (21%)
Ambp	NP_031469.1	Lipocalin	41..185	CDD:278490	33/192 (17%)
		Kunitz_BPTI	230..281	CDD:278443
		Kunitz_BPTI	285..337	CDD:278443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833096
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930