Protein Alignment CG7565 and kiaa0319

DIOPT Version :9

• Sequence 1: NP_648171.1
• Gene: CG7565 / 38893
• FlyBaseID: FBgn0035833
• Length: 1069
• Species: Drosophila melanogaster
• Sequence 2: XP_017950340.2
• Gene: kiaa0319 / 100497843
• XenbaseID: XB-GENE-6258279
• Length: 1057
• Species: Xenopus tropicalis
• Alignment Length: 1052
• Identity: 362/1052 - (34%)
• Similarity: 532/1052 - (50%)
• Gaps: 174/1052 - (16%)

  Fly   100 NCLQACCEKPRNGSSACNVVLVFKAKCYHIRCQSNEACLPKLRVRMPNEKVQMVLVNPLGDATWP 164
            :|..|||.:     |.|::..:...:||.:.||..|.|.|:....|.:.|..:..|
 Frog    52 DCTTACCNQ-----SGCDLSWMLGRRCYIVNCQHKENCEPQKVEHMKHVKSYLTFV--------- 102

  Fly   165 QLLKAEAAKQNAEILPY--------------------DEAALNFWKQPRRLSYLARNQ---ETPV 206
                   .:.:|..:|.                    ||...:|    :.||:|.:|.   |...
 Frog   103 -------LRPSARFIPLPLYGSLMSHRGYPLEENDESDEDIAHF----KELSFLNKNPSFLELAD 156

  Fly   207 YEDE------DF-PLADKRMNQMIFQPDENDVLANEELGY------YDSNAKFTTCD-------- 250
            |.:|      || ||:||     :.|.:.:|:   :.||:      :|||:  |..:
 Frog   157 YNEEYSDPKLDFLPLSDK-----VDQKENHDL---DYLGWILPETEHDSNS--TAVEIGRRNEKP 211

  Fly   251 ----METP------CPPPQQCVPLQPNAVRG-------------------------VCTCPEGFV 280
                ||.|      ...|...:.:.|..::.                         :.|.|  ||
 Frog   212 EEGLMEEPTVTADQVTEPSLLIHIPPTVIQAGGSMSDSTGTNDDAASEPTTILPIIIQTLP--FV 274

  Fly   281 WNKQRKCVMAAVPYSSYLTSNEAGQQEAAASENSPEVST-PPLKAEQN-KDIVVSVMSK-EVRLP 342
              .:|..:...:.....|::|   ...||.||.|.|.:. ||..|::. :.:.||..:: .|.||
 Frog   275 --TERTTIQEIIIEPQTLSTN---LSSAAISETSVEHTVIPPTTAKKPFQHLTVSTETEILVVLP 334

  Fly   343 EQEVTLAAFTVPDEQTSDTKYKYLWTLISQPKGPMNGTISDQSKSKVKLSNLSEGLYTFKVTVTG 407
            :.||.|.|...|:..| |..|.:.|:||.||. ...|.::.:.....|||.||.|:|..||:|:.
 Frog   335 KNEVELNAVVAPEAPT-DMPYSFEWSLIHQPV-DYQGQLNAKHARTPKLSQLSPGMYILKVSVSN 397

  Fly   408 DNGTFGEATANVTVLPENRINQPPQVIISPREQIIRQPTTNAILDGSTSTDDDKITNWHWEVISG 472
            .| :|||...||||.|. |:||||..|:||:...:..|||:||:||..||||.||..:.||.|.|
 Frog   398 LN-SFGEGYINVTVKPA-RVNQPPVAIVSPKALEMSFPTTSAIIDGRQSTDDGKIATYLWEEIEG 460

  Fly   473 P------IGYQPVLPEVNTLQLDLTSPGNYTFKLTVTDSNNVTNSTTATIAVLKETDYAPVANAG 531
            |      :|..||      |.|.....||:||:|||||:....|||||.|.|.|..||.||||||
 Frog   461 PGGEPRNVGDSPV------LHLTELITGNHTFRLTVTDNEGAINSTTAYITVSKPADYPPVANAG 519

  Fly   532 DAVILYLPNNNVTLNGTASSDDHEIVAWEWTKDASDEAKAVDMQNTRTPYVQLSNLEEGMYTFVL 596
            ...::.||.|.:.|||..||||.:||::||:...|.:.|.|.||:..:||:|:|.::.|.|||.|
 Frog   520 PDQVITLPQNAIILNGNMSSDDQKIVSYEWSLSPSSKGKVVAMQSVHSPYLQVSAMQVGKYTFEL 584

  Fly   597 KVTDGSGQSSTAKVHVFVKPPTNSPPVAEAGSNTTTSLPINWVLLNGSDSKDDIGIKSYLWKQLS 661
            .|||.|||.|:..:.|.|:|..|:||||.........||::..:|:||.|:||.||.:|.|:.:|
 Frog   585 TVTDLSGQRSSDNITVTVQPEPNTPPVAVTSPYKELILPMDSTILDGSRSRDDEGITAYKWEYIS 649

  Fly   662 GPNNAVILKSNSSIANATSLTLGLYEFELTVADENNNTATDTTWVKIVQERNAAPIANAGGDHTV 726
            ||:...|..|:..:...|.|.:|:|.|.|||.|:...::|.|..|.:.:|:|:.|.|.|||.|.:
 Frog   650 GPSKVTIQDSDKPMGLVTGLQVGVYTFHLTVKDQQGLSSTATHSVTVKKEKNSPPKACAGGTHIL 714

  Fly   727 TLPATAIYFNGSKSWDDLAVVKYLWTRDEHSLAAGVIVADTDKEPVMILTNLVQGRYVFTLTVSD 791
            .||..:|..:||||:||..:|.|||.||..|.|||.|:..:|.:|::.|||||.|.|:|.|||:|
 Frog   715 VLPDNSISLDGSKSFDDQGIVSYLWKRDAQSPAAGDIMHSSDHDPILQLTNLVDGIYIFHLTVTD 779

  Fly   792 DQGLTSSDTVSVNVRRDPKLLNLVQMTLPMGISVLVQSELDSVVQKLQLLLG---DENKIQVREL 853
            .:|.|..||.:|.||.||:..|||::.|.:|:..|.:.:.|::|::|.|||.   .:.|:|
 Frog   780 AKGETDVDTATVEVRPDPRKQNLVELILQVGVGKLTEQQKDTLVRQLALLLNVLDTDIKVQ---- 840

  Fly   854 KYDLHTD-ATVLVFYVNDGQG-KALDGLQVERQLRTQLQKD-ASILGAFAVDIRTSVCQSDCSGH 915
            |...|:| :||::|||..|.. |......|.:.|:.||.|: |..|....:.:.|:.|...||||
 Frog   841 KIAAHSDLSTVILFYVQSGHPLKVQKAANVAQTLQDQLLKEKADFLLYKVLRVDTAACLLKCSGH 905

  Fly   916 GSCNPITRACICEAFWMPS-AGYFFNNQEANCDWSILYVFVGVIVGCLLLSGVFWGIACACRQSK 979
            |.|:|||::|:|.||||.: ...:.::.|:||:||:||:.:........|.|:.|...|.|:..|
 Frog   906 GHCDPITKSCLCYAFWMENLIQRYISDGESNCEWSVLYIAIVTFAMVAFLMGIVWLCICCCQSQK 970

  Fly   980 KPRLRQKVQKYSLIGNKDEE----------------AANYSRNTSLTESETDSDVLF------ET 1022
            :.::|:|. ||:::.|.||:                |.|.|...|.:|.|:|.|.:|      ..
 Frog   971 RTKIRKKT-KYTILDNIDEQEKMELTPKYGIKHRSTAHNSSLMVSESEFESDQDTIFSREKLDRE 1034

  Fly  1023 RTKSNGLGKHKS 1034
            ..|:||:|...|
 Frog  1035 NPKTNGIGAFNS 1046

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7565	NP_648171.1	MANEC	52..153	CDD:297649	15/52 (29%)
		PKD	<454..518	CDD:214510	31/69 (45%)
		PKD	527..615	CDD:214510	41/87 (47%)
		PKD	716..805	CDD:238084	45/88 (51%)
kiaa0319	XP_017950340.2	MANEC	19..101	CDD:414795	15/53 (28%)
		PCC	<338..704	CDD:188093	162/375 (43%)
		PKD	714..793	CDD:238084	39/78 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	522	1.000	Domainoid score	I303
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H8878
Inparanoid	1	1.050	524	1.000	Inparanoid score	I1224
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D224617at33208
OrthoFinder	1	1.000	-	-		FOG0004787
OrthoInspector	1	1.000	-	-		otm48866
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2843
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060