Protein Alignment nmo and Mapk14

DIOPT Version :10

• Sequence 1: NP_001356976.1
• Gene: nmo / 38890
• FlyBaseID: FBgn0011817
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_112282.2
• Gene: Mapk14 / 81649
• RGDID: 70496
• Length: 360
• Species: Rattus norvegicus
• Alignment Length: 373
• Identity: 147/373 - (39%)
• Similarity: 206/373 - (55%)
• Gaps: 55/373 - (14%)

  Fly    36 VPQDVQPDRPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVL 100
            ||:..|...|:|.||:|.|.|..|.:.|.|||:|||...|||::.:||.:|||::|...|||||:
  Rat    20 VPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVI 84

  Fly   101 SALDILQPPH-LDFFQEIYVITELLQSDLHKIIVSPQHLSADHIKVFLYQILRGLKYLHSARILH 164
            ..||:..|.. |:.|.::|::|.|:.:||:. ||..|.|:.||::..:|||||||||:|||.|:|
  Rat    85 GLLDVFTPARSLEEFNDVYLVTHLMGADLNN-IVKCQKLTDDHVQFLIYQILRGLKYIHSADIIH 148

  Fly   165 RDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGARHYSSAVDVWSV 229
            ||:||.||.||.:|.|||.||||||..:.:    ||..|.|::||||||::...||:..||:|||
  Rat   149 RDLKPSNLAVNEDCELKILDFGLARHTDDE----MTGYVATRWYRAPEIMLNWMHYNQTVDIWSV 209

  Fly   230 GCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAPKPPSFSVLYTL 294
            |||..|||..|.||...:.:.||:.|..|.|||.            .:::.|.|...:.:.:.:|
  Rat   210 GCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPP------------AYLINRMPSHEARNYIQSL 262

  Fly   295 SS-----------HATHEAVHLLCQMLVFDPDKRISVTDALAHPYLDEGRLRYHSCMCKCCFTTS 348
            :.           .|...||.||.:|||.|.||||:...||||.|.    .:||.
  Rat   263 AQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYF----AQYHD---------- 313

  Fly   349 AGMRQYTADFEPSAGQPFDDLWERKLTSVQQVK----EEMHKFIAEQL 392
                   .|.||.| .|:|..:|.:...:.:.|    :|:..|:...|
  Rat   314 -------PDDEPVA-DPYDQSFESRDLLIDEWKSLTYDEVISFVPPPL 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmo	NP_001356976.1	STKc_NLK	39..411	CDD:173748	145/370 (39%)
Mapk14	NP_112282.2	STKc_p38alpha	6..350	CDD:143382	146/368 (40%)