Protein Alignment nmo and Mapk11

DIOPT Version :10

• Sequence 1: NP_001356976.1
• Gene: nmo / 38890
• FlyBaseID: FBgn0011817
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: XP_017450608.1
• Gene: Mapk11 / 689314
• RGDID: 1309340
• Length: 371
• Species: Rattus norvegicus
• Alignment Length: 377
• Identity: 152/377 - (40%)
• Similarity: 226/377 - (59%)
• Gaps: 46/377 - (12%)

  Fly    36 VPQDVQPDRPIGYGAFGVVW-------AVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCF 93
            |||.:|..||:|.||:|.||       :..|.|..::||:|||...||||:.::|.:|||::|..
  Rat    20 VPQRLQGLRPVGSGAYGSVWSHPGPPHSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKH 84

  Fly    94 FKHENVLSALDILQP-PHLDFFQEIYVITELLQSDLHKIIVSPQHLSADHIKVFLYQILRGLKYL 157
            .|||||:..||:..| ..::.|.|:|::|.|:.:||:. ||..|.||.:|::..:||:||||||:
  Rat    85 LKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNN-IVKCQALSDEHVQFLVYQLLRGLKYI 148

  Fly   158 HSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGARHYSS 222
            |||.|:|||:||.|:.||.:|.|:|.||||||..:    :.||..|.|::||||||::...||:.
  Rat   149 HSAGIIHRDLKPSNVAVNEDCELRILDFGLARQAD----EEMTGYVATRWYRAPEIMLNWMHYNQ 209

  Fly   223 AVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDM-RHACEGARTHMLRRAPKPP 286
            .||:||||||..|||..:.||...:.:.||:.|.|::|||:.|.: :.:.|.|||::....|.|.
  Rat   210 TVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQ 274

  Fly   287 SFSVLYTLSS--HATHE-AVHLLCQMLVFDPDKRISVTDALAHPYLDEGRLRYHSCMCKCCFTTS 348
            .     .|||  |..:. ||.||.:|||.|.|:|:|..:||||.|..:    ||.
  Rat   275 K-----DLSSVFHGANPLAVDLLGRMLVLDSDQRVSAAEALAHAYFSQ----YHD---------- 320

  Fly   349 AGMRQYTADFEPSAGQPFDDLWERKLTSVQQVKEEMHKFIA--EQLQTGRVP 398
                   .|.||.| :|:|:..|.|..::::.||..::.:.  :.|:|.::|
  Rat   321 -------PDDEPEA-EPYDESVEAKERTLEEWKELTYQEVLSFKPLETSQLP 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmo	NP_001356976.1	STKc_NLK	39..411	CDD:173748	149/374 (40%)
Mapk11	XP_017450608.1	Protein Kinases, catalytic domain	8..357	CDD:473864	149/368 (40%)