Protein Alignment nmo and MAPK13

DIOPT Version :9

• Sequence 1: NP_001356976.1
• Gene: nmo / 38890
• FlyBaseID: FBgn0011817
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_002745.1
• Gene: MAPK13 / 5603
• HGNCID: 6875
• Length: 365
• Species: Homo sapiens
• Alignment Length: 346
• Identity: 131/346 - (37%)
• Similarity: 198/346 - (57%)
• Gaps: 33/346 - (9%)

  Fly    46 IGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQP-P 109
            :|.||:|.|.:..|.|.|.:||:|||...|||.:.:||.:|||.:|...:||||:..||:..| .
Human    31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPAS 95

  Fly   110 HLDFFQEIYVITELLQSDLHKIIVSPQHLSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLV 174
            .|..|.:.|::...:|:||.||:  ....|.:.|:..:||:|:||||:|||.::|||:|||||.|
Human    96 SLRNFYDFYLVMPFMQTDLQKIM--GMEFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAV 158

  Fly   175 NSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGR 239
            |.:|.|||.||||||..:.:    ||..|||::|||||:::...||:..||:||||||..|:|..
Human   159 NEDCELKILDFGLARHADAE----MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTG 219

  Fly   240 RILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAPKPP--SFSVLYTLSSHATHEA 302
            :.||:.::.:.||..|.::.|.|..|.::...:.|....::..|:.|  .|:.|:   ..|:.:|
Human   220 KTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLF---PRASPQA 281

  Fly   303 VHLLCQMLVFDPDKRISVTDALAHPYLDEGRLRYHSCMCKCCFTTSAGMRQYTADFEPSAGQPFD 367
            ..||.:||..|.|||::...||.||:.:..|                     ..:.|..|.||||
Human   282 ADLLEKMLELDVDKRLTAAQALTHPFFEPFR---------------------DPEEETEAQQPFD 325

  Fly   368 DLWERKLTSVQQVKEEMHKFI 388
            |..|.:..:|.:.|:.::|.|
Human   326 DSLEHEKLTVDEWKQHIYKEI 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmo	NP_001356976.1	STKc_NLK	39..411	CDD:173748	131/346 (38%)
MAPK13	NP_002745.1	STKc_p38delta	9..351	CDD:143384	131/346 (38%)
		TXY	180..182		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143091
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840