Protein Alignment nmo and mapk12

DIOPT Version :10

• Sequence 1: NP_001356976.1
• Gene: nmo / 38890
• FlyBaseID: FBgn0011817
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_001017080.1
• Gene: mapk12 / 549834
• XenbaseID: XB-GENE-485782
• Length: 363
• Species: Xenopus tropicalis
• Alignment Length: 359
• Identity: 137/359 - (38%)
• Similarity: 207/359 - (57%)
• Gaps: 40/359 - (11%)

  Fly    46 IGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQPPH 110
            :|.||:|.|.:..|.|.|.:||:|||...|||.:.:||.:|||::|...:||||:..||:..|..
 Frog    33 VGSGAYGTVCSSLDTRTGTKVAIKKLYRPFQSELFAKRAYRELRLLKHMQHENVIGLLDVFTPDS 97

  Fly   111 -LDFFQEIYVITELLQSDLHKIIVSPQHLSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLV 174
             |:.|.:.|::...:.:||.| |:..:.||.|.|:..:|||||||||:|||.|:|||:|||||.|
 Frog    98 TLENFNDFYLVMPFMGTDLGK-IMKHEKLSEDRIQFLVYQILRGLKYIHSAGIIHRDLKPGNLAV 161

  Fly   175 NSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGR 239
            |.:|.|||.||||||..:.:    ||..|||::|||||:::...||:..||:||||||..|:...
 Frog   162 NEDCELKILDFGLARHTDSE----MTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMYTG 222

  Fly   240 RILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAPK--PPSFSVLYTLSSHATHEA 302
            |.||:..:.:.||..|.::.||||.:.::........:.::..||  ...|.   :|..:|...|
 Frog   223 RPLFKGNDHLDQLTEIMKITGTPTQDFVQKLQSPDAKNYIKSLPKVQKKDFG---SLLRYANPLA 284

  Fly   303 VHLLCQMLVFDPDKRISVTDALAHPYLDEGRLRYHSCMCKCCFTTSAGMRQYTADFEPSAGQPFD 367
            |::|.:|||.|.:|||:.|:||||||.::    :|.                 .|.|..| :|:|
 Frog   285 VNILEKMLVLDAEKRITATEALAHPYFEQ----FHD-----------------IDDETEA-EPYD 327

  Fly   368 DLWERKLTSVQQVKEEMHK-------FIAEQLQT 394
            |.::.....:::.:...||       .:|:..:|
 Frog   328 DSFDNVNLPLEEWRRLTHKELTSYKPLVADSKET 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmo	NP_001356976.1	STKc_NLK	39..411	CDD:173748	137/359 (38%)
mapk12	NP_001017080.1	STKc_p38gamma	11..353	CDD:143385	135/349 (39%)