Protein Alignment nmo and Mapk4

DIOPT Version :10

• Sequence 1: NP_001356976.1
• Gene: nmo / 38890
• FlyBaseID: FBgn0011817
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_062192.1
• Gene: Mapk4 / 54268
• RGDID: 3047
• Length: 583
• Species: Rattus norvegicus
• Alignment Length: 419
• Identity: 122/419 - (29%)
• Similarity: 205/419 - (48%)
• Gaps: 88/419 - (21%)

  Fly    44 RPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQP 108
            :|:|:|..|:|.:.||.|..|:||:||:  |.....|.|...||:|::....|:|::...::|.|
  Rat    24 QPLGFGVNGLVLSATDSRACRKVAVKKI--VLSDARSMKHALREIKIIRRLDHDNIVKVYEVLGP 86

  Fly   109 PHLDF------FQEIYVITELLQSDLHKIIVSPQHLSADHIKVFLYQILRGLKYLHSARILHRDI 167
            ...|.      |...|::.|.:::|| ..::....|:.:|.|:|:||:||||||:|||.:||||:
  Rat    87 KGSDLQGELFKFSVAYIVQEYMETDL-ACLLEQGTLTEEHAKLFMYQLLRGLKYIHSANVLHRDL 150

  Fly   168 KPGNLLVNS-NCVLKICDFGLARVEEPDQAK--HMTQEVVTQYYRAPEILMGARHYSSAVDVWSV 229
            ||.|:.::: :.||||.||||||:.:...:.  ::::.:||::||:|.:|:...:|:.|:|:|:.
  Rat   151 KPANIFISTEDLVLKIGDFGLARIADQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAA 215

  Fly   230 GCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAP---------KP 285
            |||..|:|..::||...:.::|::||.:.:.....||        :..:||..|         |.
  Rat   216 GCILAEMLTGKMLFAGAHELEQMQLILDTIPVVREED--------KEELLRVMPSFVSSTWEVKR 272

  Fly   286 PSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPYLDEGRLRYHSCMCKCCFTTSAG 350
            |    |..|......||:..|.::|.|:|..|::....|.|||:..     :||
  Rat   273 P----LRKLLPDVNREAIDFLEKILTFNPMDRLTAEMGLQHPYMSP-----YSC----------- 317

  Fly   351 MRQYTADFEPSAGQPF------DDL------------WERKLTSV-----------QQVKEEMHK 386
                 .:.||::..||      |||            |:|...|:           |...|
  Rat   318 -----PEDEPTSQHPFRIEDEIDDLVLMAASQSQLSNWDRYPVSLSSDLEWRPDRCQDASE---- 373

  Fly   387 FIAEQLQTGRVPLCINPQSAAFKSFASST 415
             :....:.|..||..:.|....|...||:
  Rat   374 -VQRDPRAGSTPLAEDVQVDPRKDSQSSS 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmo	NP_001356976.1	STKc_NLK	39..411	CDD:173748	120/413 (29%)
Mapk4	NP_062192.1	STKc_MAPK4_6	14..351	CDD:143359	110/362 (30%)