DRSC/TRiP Functional Genomics Resources

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Protein Alignment nmo and mapk3

DIOPT Version :10

Sequence 1:NP_001356976.1 Gene:nmo / 38890 FlyBaseID:FBgn0011817 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_958915.1 Gene:mapk3 / 399480 ZFINID:ZDB-GENE-040121-1 Length:392 Species:Danio rerio


Alignment Length:398 Identity:151/398 - (37%)
Similarity:227/398 - (57%) Gaps:53/398 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 GGAAGGAPQGASAILAAAAPYYQPPAVPQ------DVQPD----RPIGYGAFGVVWAVTDPRDGR 64
            |..|.|.|.||:.         ..|.:..      ||.|.    :.||.||:|:|.:..|..:..
Zfish    25 GAVAPGGPSGAAG---------SKPGLESVKGQNFDVGPRYTDLQYIGEGAYGMVCSAFDNVNKI 80

  Fly    65 RVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQPPHLDFFQEIYVITELLQSDLH 129
            |||:||: :.|:.....:|..||:|:|..|.|||::...|||:..|:|:.:::|::.:|:::||:
Zfish    81 RVAIKKI-SPFEHQTYCQRTLREIKILLRFHHENIIGINDILRARHIDYMRDVYIVQDLMETDLY 144

  Fly   130 KIIVSPQHLSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEP- 193
            |:: ..|.||.|||..|||||||||||:|||.:||||:||.|||:|:.|.||||||||||:.:| 
Zfish   145 KLL-KTQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPE 208

  Fly   194 -DQAKHMTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITE 257
             |....:|:.|.|::||||||::.::.|:.::|:||||||..|:|..|.:|..::.:.||..|..
Zfish   209 HDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILG 273

  Fly   258 LLGTPTMEDMRHACEGARTHMLRRAPKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTD 322
            :||:|:.:|:.........:.|:..|:.|... ...|...|.::|:.||.:||.|:|.|||:|..
Zfish   274 VLGSPSQDDLNCIINMKARNYLQSLPQKPKIP-WNKLFPKADNKALDLLDRMLTFNPLKRINVEQ 337

  Fly   323 ALAHPYLDEGRLRYHSCMCKCCFTTSAGMRQYTADFEPSAGQPF------DDLWERKLTSVQQVK 381
            |||||||::                     .|....||.|.:||      |||.:.||..:  :.
Zfish   338 ALAHPYLEQ---------------------YYDPSDEPVAEEPFTFNMELDDLPKEKLKEL--IF 379

  Fly   382 EEMHKFIA 389
            ||..:|.|
Zfish   380 EETARFQA 387

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nmoNP_001356976.1 STKc_NLK 39..411 CDD:173748 144/363 (40%)
mapk3NP_958915.1 STKc_ERK1_2_like 50..384 CDD:270839 142/359 (40%)

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