Protein Alignment nmo and Mapk1

DIOPT Version :10

• Sequence 1: NP_001356976.1
• Gene: nmo / 38890
• FlyBaseID: FBgn0011817
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_036079.1
• Gene: Mapk1 / 26413
• MGIID: 1346858
• Length: 358
• Species: Mus musculus
• Alignment Length: 380
• Identity: 152/380 - (40%)
• Similarity: 223/380 - (58%)
• Gaps: 43/380 - (11%)

  Fly    22 AILAAAAPYYQPPAVPQDVQPDRP----IGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSK 82
            |..|||.|......| .||.|...    ||.||:|:|.:..|..:..|||:||: :.|:.....:
Mouse     2 AAAAAAGPEMVRGQV-FDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKI-SPFEHQTYCQ 64

  Fly    83 RVFRELKMLCFFKHENVLSALDILQPPHLDFFQEIYVITELLQSDLHKIIVSPQHLSADHIKVFL 147
            |..||:|:|..|:|||::...||::.|.::..:::|::.:|:::||:|:: ..||||.|||..||
Mouse    65 RTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLL-KTQHLSNDHICYFL 128

  Fly   148 YQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEP--DQAKHMTQEVVTQYYRA 210
            |||||||||:|||.:||||:||.|||:|:.|.|||||||||||.:|  |....:|:.|.|::|||
Mouse   129 YQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRA 193

  Fly   211 PEILMGARHYSSAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACE-GA 274
            |||::.::.|:.::|:||||||..|:|..|.:|..::.:.||..|..:||:|:.||:..... .|
Mouse   194 PEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKA 258

  Fly   275 RTHMLRRAPKPPSFSVLYT-LSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPYLDEGRLRYHS 338
            |.::|   ..|....|.:. |..:|..:|:.||.:||.|:|.|||.|..|||||||::
Mouse   259 RNYLL---SLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQ------- 313

  Fly   339 CMCKCCFTTSAGMRQYTADFEPSAGQPF------DDLWERKLTSVQQVKEEMHKF 387
                          .|....||.|..||      |||.:.||..:  :.||..:|
Mouse   314 --------------YYDPSDEPIAEAPFKFDMELDDLPKEKLKEL--IFEETARF 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmo	NP_001356976.1	STKc_NLK	39..411	CDD:173748	146/363 (40%)
Mapk1	NP_036079.1	STKc_ERK1_2_like	17..351	CDD:270839	145/361 (40%)
		TXY	183..185		1/1 (100%)