Protein Alignment nmo and Mapk11

DIOPT Version :10

• Sequence 1: NP_001356976.1
• Gene: nmo / 38890
• FlyBaseID: FBgn0011817
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_035291.4
• Gene: Mapk11 / 19094
• MGIID: 1338024
• Length: 364
• Species: Mus musculus
• Alignment Length: 400
• Identity: 155/400 - (38%)
• Similarity: 229/400 - (57%)
• Gaps: 61/400 - (15%)

  Fly    36 VPQDVQPDRPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVL 100
            |||.:|..||:|.||:|.|.:..|.|..::||:|||...||||:.::|.:|||::|...|||||:
Mouse    20 VPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVI 84

  Fly   101 SALDILQP-PHLDFFQEIYVITELLQSDLHKIIVSPQHLSADHIKVFLYQILRGLKYLHSARILH 164
            ..||:..| ..::.|.|:|::|.|:.:||:. ||..|.||.:|::..:||:||||||:|||.|:|
Mouse    85 GLLDVFTPATSIEDFSEVYLVTTLMGADLNN-IVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIH 148

  Fly   165 RDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGARHYSSAVDVWSV 229
            ||:||.|:.||.:|.|:|.||||||..:    :.||..|.|::||||||::...||:..||:|||
Mouse   149 RDLKPSNVAVNEDCELRILDFGLARQAD----EEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSV 209

  Fly   230 GCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDM-RHACEGARTHMLRRAPKPPSFSVLYT 293
            |||..|||..:.||...:.:.||:.|.|::|||:.|.: :.:.|.|||::....|.|..     .
Mouse   210 GCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQK-----D 269

  Fly   294 LSS--HATHE-AVHLLCQMLVFDPDKRISVTDALAHPYLDEGRLRYHSCMCKCCFTTSAGMRQYT 355
            |||  |..:. |:.||.:|||.|.|:|:|..:||||.|..:    ||.
Mouse   270 LSSVFHGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQ----YHD----------------- 313

  Fly   356 ADFEPSAGQPFDDLWERKLTSVQQVKEEMHKFIAEQLQTGRVPLCINPQSAAFKSFASSTVAHPS 420
            .|.||.| :|:|:..|.|..::::.||..::                 :..:||..      .||
Mouse   314 PDDEPEA-EPYDESVEAKERTLEEWKELTYQ-----------------EVLSFKPL------EPS 354

  Fly   421 ELPPSPHQWE 430
            :| |..|:.|
Mouse   355 QL-PGTHEIE 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmo	NP_001356976.1	STKc_NLK	39..411	CDD:173748	146/376 (39%)
Mapk11	NP_035291.4	Protein Kinases, catalytic domain	8..350	CDD:473864	148/378 (39%)
		TXY	180..182		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	312..331		8/36 (22%)