Protein Alignment nmo and lit-1

DIOPT Version :10

• Sequence 1: NP_001356976.1
• Gene: nmo / 38890
• FlyBaseID: FBgn0011817
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_001022805.1
• Gene: lit-1 / 176808
• WormBaseID: WBGene00003048
• Length: 634
• Species: Caenorhabditis elegans
• Alignment Length: 422
• Identity: 267/422 - (63%)
• Similarity: 330/422 - (78%)
• Gaps: 11/422 - (2%)

  Fly    17 PQ----GASAILAAAAPYYQPPAVPQDVQPDRPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQS 77
            ||    .::||||||.|:|.||.  ||.|||||||||||||||:|||||.|:||||||:|||||:
 Worm   215 PQVAHVSSNAILAAAQPFYPPPV--QDSQPDRPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQN 277

  Fly    78 LVSSKRVFRELKMLCFFKHENVLSALDILQPPHLDFFQEIYVITELLQSDLHKIIVSPQHLSADH 142
            |.|.||||||:|||..|:|:||||.||||||.:..||||:||:|||:||||||||||||.|:.||
 Worm   278 LASCKRVFREIKMLSSFRHDNVLSLLDILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPDH 342

  Fly   143 IKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMTQEVVTQY 207
            :|||:|||||||||||:|.|||||||||||||||||:||||||||||..:.....:||.||||||
 Worm   343 VKVFVYQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQY 407

  Fly   208 YRAPEILMGARHYSSAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACE 272
            |||||:|||||.|:.|||:|||||||.|||.|:|||||..|::||::|.:|||||:.|.|::|||
 Worm   408 YRAPELLMGARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACE 472

  Fly   273 GARTHMLRRAPKPPSFSVLYTLSS--HATHEAVHLLCQMLVFDPDKRISVTDALAHPYLDEGRLR 335
            ||:.|:||...:.|....||.::|  ...||||.||.::|.|||||||||.:||.|.||:|||||
 Worm   473 GAKNHVLRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYLEEGRLR 537

  Fly   336 YHSCMCKCCFT-TSAGMRQYTADFEPSAGQPFDDLWERKLT--SVQQVKEEMHKFIAEQLQTGRV 397
            :|||||.||:| .:...|.:..|.:|....|||..||:.::  |:.:::|:|::|:.::.....|
 Worm   538 FHSCMCSCCYTKPNMPSRLFAQDLDPRHESPFDPKWEKDMSRLSMFELREKMYQFVMDRPALYGV 602

  Fly   398 PLCINPQSAAFKSFASSTVAHPSELPPSPHQW 429
            .|||||||||:|:||||:||..|||||||..|
 Worm   603 ALCINPQSAAYKNFASSSVAQASELPPSPQAW 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nmo	NP_001356976.1	STKc_NLK	39..411	CDD:173748	240/376 (64%)
lit-1	NP_001022805.1	STKc_NLK	239..616	CDD:173748	240/376 (64%)