DRSC/TRiP Functional Genomics Resources

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Protein Alignment nmo and Mapk8

DIOPT Version :9

Sequence 1:NP_001356976.1 Gene:nmo / 38890 FlyBaseID:FBgn0011817 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_446281.2 Gene:Mapk8 / 116554 RGDID:621506 Length:427 Species:Rattus norvegicus


Alignment Length:400 Identity:143/400 - (35%)
Similarity:216/400 - (54%) Gaps:57/400 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 RPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQP 108
            :|||.||.|:|.|..|....|.||:|||...||:...:||.:|||.::....|:|::..|::..|
  Rat    30 KPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTP 94

  Fly   109 -PHLDFFQEIYVITELLQSDLHKIIVSPQHLSADH--IKVFLYQILRGLKYLHSARILHRDIKPG 170
             ..|:.||::|::.||:.::|.::|    .:..||  :...|||:|.|:|:||||.|:|||:||.
  Rat    95 QKSLEEFQDVYIVMELMDANLCQVI----QMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPS 155

  Fly   171 NLLVNSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGE 235
            |::|.|:|.|||.||||||.  ...:..||..|||:||||||:::| ..|...||:||||||.||
  Rat   156 NIVVKSDCTLKILDFGLART--AGTSFMMTPYVVTRYYRAPEVILG-MGYKENVDLWSVGCIMGE 217

  Fly   236 LLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAPKPPSFS-------VLYT 293
            ::..:|||..::.:.|...:.|.||||..|.|:......||::..| ||...:|       ||:.
  Rat   218 MVCLKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENR-PKYAGYSFEKLFPDVLFP 281

  Fly   294 LSSH----ATHEAVHLLCQMLVFDPDKRISVTDALAHPYLDEGRLRYHSCMCKCCFTTSAGMRQY 354
            ..|.    ...:|..||.:|||.|..|||||.:||.|||::                        
  Rat   282 ADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYIN------------------------ 322

  Fly   355 TADFEPSAGQ------PFDDLWERKLTSVQQVKEEMHKFI---AEQLQTGRVPLCINPQSAAFKS 410
             ..::||..:      |...|.||:.| :::.||.::|.:   .|:.:.|.:....:|..||..:
  Rat   323 -VWYDPSEAEAPPPKIPDKQLDEREHT-IEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVIN 385

  Fly   411 FASSTVAHPS 420
            .:...|:.||
  Rat   386 GSQHPVSSPS 395

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nmoNP_001356976.1 STKc_NLK 39..411 CDD:173748 140/389 (36%)
Mapk8NP_446281.2 STKc_JNK 25..360 CDD:270840 135/363 (37%)
S_TKc 26..321 CDD:214567 124/298 (42%)
TXY 183..185 1/1 (100%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 368..411 6/27 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166336792
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D741207at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.850

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