DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8209 and SPAC17C9.11c

DIOPT Version :9

Sequence 1:	NP_648167.1	Gene:	CG8209 / 38888	FlyBaseID:	FBgn0035830	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_594595.1	Gene:	SPAC17C9.11c / 2542167	PomBaseID:	SPAC17C9.11c	Length:	240	Species:	Schizosaccharomyces pombe

Alignment Length:	249	Identity:	80/249 - (32%)
Similarity:	122/249 - (48%)	Gaps:	28/249 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 LKCDECGKVLRDHTEVEYHAAKTGHTKFSESEEEKKALTEEEKKAQLALIEEKLKQKRIEREERE 153
            |||.||.|:|......|:|:.||.|.:|.|:|||.|..:.||.|..:..:.||.|:|:    |:|
pombe     3 LKCLECDKLLSSIEMAEFHSTKTSHDQFEETEEEIKKRSPEELKQAIEALREKAKEKK----EKE 63

  Fly   154 KIEALQREKNRI----KSGKDMTEAKRRMEELEMKKIVEQRKREKDEEKAARDRVKAQIEADKAA 214
            :|.||:.:|...    ||..:..:|.|:|::....:.:::.:::|.|:...|.::.|:||.||..
pombe    64 RILALEEKKTNYKILQKSNDETAQAMRKMQDQARLRDLQKIRQQKAEDAEQRKKILAEIERDKKR 128

  Fly   215 RKA-REQKELGNAEPAPSV--------SSTTVSSPPAGVKSPPRDYTETRIQVRLQDGSTLQETF 270
            |.| ||.|.....|.|..:        |||...:||          |..|..:| .||.....|.
pombe   129 RAAERENKNSSVKETAAPIKQPKNANSSSTCTRTPP----------TSGRFSIR-HDGQVCNITI 182

  Fly   271 NVKEQLSAVRVFIQMKTGIESPFSLMTTFPRKLFAEDDYEKPLEVLGLVPSAVI 324
            ..:|.|..:...:..|..:..|....|||||..:..|.::||:..|.|.||||:
pombe   183 AAEETLRQLAQQVAEKMNVSPPTKFTTTFPRASYGTDVFDKPVNQLDLFPSAVL 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8209	NP_648167.1	UBA_UBXN1	2..42	CDD:270487
CG8209	NP_648167.1	SAKS1_UBX	250..328	CDD:176367	24/75 (32%)
SPAC17C9.11c	NP_594595.1	UBQ	174..239	CDD:294102	21/63 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	87	1.000	Domainoid score	I2152
eggNOG	1	0.900	-	-		E1_KOG2689
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9283
Inparanoid	1	1.050	119	1.000	Inparanoid score	I1506
OMA	1	1.010	-	-		QHG52921
OrthoFinder	1	1.000	-	-		FOG0003698
OrthoInspector	1	1.000	-	-		oto100760
orthoMCL	1	0.900	-	-		OOG6_104595
Panther	1	1.100	-	-	LDO	PTHR46340
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2329
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.900