DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8209 and si:ch73-173p19.1

DIOPT Version :9

Sequence 1:	NP_648167.1	Gene:	CG8209 / 38888	FlyBaseID:	FBgn0035830	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	XP_002660968.3	Gene:	si:ch73-173p19.1 / 100332407	ZFINID:	ZDB-GENE-130530-952	Length:	918	Species:	Danio rerio

Alignment Length:	337	Identity:	77/337 - (22%)
Similarity:	132/337 - (39%)	Gaps:	94/337 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VQTLMDMGFPRERVEYALEVTSNKGVEPAMEWLLAHVDDPIPSRQGAGESPGSTAQPAAAVDSSA 68
            :.||.:|||..::::.|:: .....|..|.||||          ||.........||:..::::.
Zfish    11 ISTLTEMGFSHDQIQAAMQ-AGFFSVTEAAEWLL----------QGGSPRHKLVKQPSGPLETAF 64

  Fly    69 AA------ASSSTSGAGETSAPVAKSLKCDECGKVLRDHTEVEYHAAKTGHTKFSESEEEKKALT 127
            :|      |:||.:.:..|...:..:                                  ..::.
Zfish    65 SAFNPPKDAASSNNNSEATGPSLVLA----------------------------------PPSVN 95

  Fly   128 EEEKKAQLALIEEKLKQKR--IEREEREKIEALQREKNRIKSGKDMTEAKRRMEELEMKKIVEQR 190
            .:..|.||.| |.::||.:  ...::|:|:....|.:.|         .|::..||.:|:|.|.|
Zfish    96 AQTTKEQLPL-ETRIKQDKSNFHEQQRQKVAQEARAERR---------QKKQERELVLKRIAEDR 150

  Fly   191 KREKDEEKAARDRVKAQIE--ADKAARKAREQKELGNAEPAPSVSSTTVSSPPAGVKSPPRDYTE 253
            :.:::         |||.|  ||.:...|:.|:..|..|  .||.:..:
Zfish   151 RSQQE---------KAQTEATADTSPSSAQGQRLGGRVE--TSVDNHCI---------------- 188

  Fly   254 TRIQVRLQDGSTLQETFNVKEQLSAVRVFIQMKTGIESPFSLMTTFPRKLFAEDDYEKPLEVLGL 318
              :.:||..|.:::|.|.....||.|..:|..:......|||:..||||.|.|.:....|..|||
Zfish   189 --LMIRLPSGESMRERFPADTPLSQVVEYIASRHPSLPAFSLLQGFPRKRFGETELTCSLRSLGL 251

  Fly   319 VPSAVITMTKTP 330
            .|:|.:.:..||
Zfish   252 TPNAALCIQTTP 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8209	NP_648167.1	UBA_UBXN1	2..42	CDD:270487	12/37 (32%)
CG8209	NP_648167.1	SAKS1_UBX	250..328	CDD:176367	24/77 (31%)
si:ch73-173p19.1	XP_002660968.3	UBA_like_SF	6..43	CDD:304366	10/32 (31%)
		Nop25	116..>169	CDD:286843	17/70 (24%)
		UBQ	187..260	CDD:294102	24/90 (27%)
		AMN1	523..701	CDD:187754
		LRR	<524..710	CDD:227223
		leucine-rich repeat	545..569	CDD:275381
		leucine-rich repeat	570..594	CDD:275381
		leucine-rich repeat	595..620	CDD:275381
		leucine-rich repeat	621..645	CDD:275381
		leucine-rich repeat	646..691	CDD:275381
		leucine-rich repeat	692..766	CDD:275381
		leucine-rich repeat	717..742	CDD:275381
		AMN1	750..>888	CDD:187754
		leucine-rich repeat	767..790	CDD:275381
		leucine-rich repeat	791..815	CDD:275381
		leucine-rich repeat	816..840	CDD:275381
		leucine-rich repeat	841..863	CDD:275381
		leucine-rich repeat	864..888	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2689
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2329
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.800