Protein Alignment CG8042 and Ubxn4

DIOPT Version :10

• Sequence 1: NP_648165.1
• Gene: CG8042 / 38886
• FlyBaseID: FBgn0027554
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: XP_006249761.1
• Gene: Ubxn4 / 304766
• RGDID: 1307451
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 680
• Identity: 193/680 - (28%)
• Similarity: 283/680 - (41%)
• Gaps: 199/680 - (29%)

  Fly     1 MNWHKGNIAEAVAASKAKGAVFVVFIEGQDEMTRKLERFVDDSQVRSRLETSDFVAIKVQGNSSA 65
            |.|.:|.|..|:|::|..|||||||:.|.||.:.::....:|.:|| ...:.:|||||:...|.|
  Rat     1 MLWFQGAIPAAIASAKRSGAVFVVFVAGDDEQSTQMAASWEDEKVR-EASSDNFVAIKIDTKSEA 64

  Fly    66 YGQFMSLYKIVPIPSLFFIGKTGTPLEIATGVTASVDELTEKIDKVLILAGKRTEPVAASSSSCA 130
            ..||..:|.:|.:||.||||.:|.|||:..| :.|.|||..:|.||..:...:.|
  Rat    65 CLQFSQIYPVVCVPSSFFIGDSGIPLEVIAG-SVSADELVTRIHKVQQMHSLKGE---------- 118

  Fly   131 KTLDPNEVRSFAGADGSSSTGESQVVQTASENFRDPETTSVSNSPTGGVEEAKTNPPNSPVAASL 195
             |...|:.:|.:.....|::.|..:.::|     :...|.:..:||       |:.|.|..||.
  Rat   119 -TSVTNDKQSESSVSTPSASFEPDICESA-----ESRNTELCETPT-------TSDPKSDTAAG- 169

  Fly   196 ASIPAAVSTSSLEGKSGSEAEAASPTALAAEKRAAASKVEGSATTSGAAARNFATNNLIPAVPLM 260
                               .|.|...:|:.|....::
  Rat   170 -------------------GECAGHDSLSQEPPGCSN---------------------------- 187

  Fly   261 TPAVPVPTQRPLEAQDNT-ESEERLAEVRNILEQKRKERVEEEKRMEKENELRRRRDGREAQSQQ 324
                    |||  |:|.| ..|.||.:.   ||::|:|:.:||.:.|.:.|:.||:.|:|....:
  Rat   188 --------QRP--AEDLTVRVESRLTKK---LEERREEKRKEEAQREIKKEIERRKTGKEMLDYK 239

  Fly   325 ARAKEQELKNMQEQIKRERQEELAARERIRAQIAADRAEQAQRFNTPDISSTTNSVAATAASNVI 389
            .:.:|:..|.|.|:..||:.|:.||||||:.|||.||||:|.||     :.|..:.||.||:.:.
  Rat   240 RKQEEELTKRMLEERSREKAEDRAARERIKQQIALDRAERAARF-----AKTKEAEAAKAAALLA 299

  Fly   390 -TTDASVSSVDET-------RLQIRLPGGIQRTKSFPAGEVLATVRVYVRNEMLAASDVRDFTLA 446
             ..:|.|.....|       |:|.|||.|...|..||:...|...|.:....:  .:...:|:||
  Rat   300 KQAEAEVKRESSTRDRSTIARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTV--GNTYGNFSLA 362

  Fly   447 TSYPRREFQTEDEVKTLNELNLVPNAVVLVLT--KEQVNRVVQSGGSLMTMLGTV------IWAL 503
            |.:|||||..||..:.|.:|.|.|:|.|::|.  :...:.|..|.|.:.|:||||      ||.|
  Rat   363 TMFPRREFTREDYKRKLLDLELAPSASVVLLPAGRPATSIVPSSSGDIWTLLGTVLYPFLAIWRL 427

  Fly   504 LTPAAKAFDYINKMGLRPLTQKLSVFMANFRWPGQRAGLEVYQGDAAARRNMDMFSLRPTPAPGY 568
            :                          :||                       :|| .|.||
  Rat   428 I--------------------------SNF-----------------------LFS-NPPPA--- 439

  Fly   569 EYDGASTEQTGGSAERPTPQNQPGPGNTPPAHNTSQASASQSQQFQQRP--------GGYQPPKY 625
                    ||...|....|.|                |||.|:..::.|        .|....|.
  Rat   440 --------QTSARATSTEPSN----------------SASSSKSEKREPVRKRVLEKRGEDFKKE 480

  Fly   626 GDSNIRRLQDTKKDEKDKDKATYNGNSTQQ 655
            |.....|.||..:||.:    |:|||||||
  Rat   481 GKIYRLRTQDDGEDENN----TWNGNSTQQ 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8042	NP_648165.1	PRK10263	<165..>369	CDD:236669	55/204 (27%)
		TPH	<269..>367	CDD:464007	42/98 (43%)
		Ubl1_cv_Nsp3_N-like	399..476	CDD:475130	29/83 (35%)
Ubxn4	XP_006249761.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	4..113	CDD:469754	47/110 (43%)
		UBX_UBXN4	318..394	CDD:340534	28/77 (36%)