Protein Alignment CG8042 and ubxn-4

DIOPT Version :10

• Sequence 1: NP_648165.1
• Gene: CG8042 / 38886
• FlyBaseID: FBgn0027554
• Length: 656
• Species: Drosophila melanogaster
• Sequence 2: NP_001370812.1
• Gene: ubxn-4 / 176187
• WormBaseID: WBGene00022703
• Length: 469
• Species: Caenorhabditis elegans
• Alignment Length: 672
• Identity: 146/672 - (21%)
• Similarity: 248/672 - (36%)
• Gaps: 223/672 - (33%)

  Fly     1 MNWHKGNIAEAVAASKAKGAVFVVFIEGQDEMTRKLERF---VDDSQVRSRLETSDFVAIKVQGN 62
            |.|..||:|.|:..|:...|:.:|:|....|..:..:.|   :|.|.:...:     |.||::..
 Worm     1 MQWFGGNVATAIQISRKNKALLIVYITTDSEDGQIFDGFWQHIDSSNLLCAV-----VGIKLKAG 60

  Fly    63 SSAYGQFMSLYKIVPIPSLFFIGKTGTPLEIATG-VTASVDELTEKIDKVLILAGKRTEPVAASS 126
            .::..||..:|....:|:.:.|.:.|.|||:.|. |..:.|:...|.||
 Worm    61 ETSAQQFADIYPTPILPAAYLIDQNGKPLEVITPLVGKTYDQFRAKFDK---------------- 109

  Fly   127 SSCAKTLDPNEVRSFAGADGSSSTGESQVVQTASENFRDPETTSVSNSPTGGVEEAKT-NPPNSP 190
                                            |:..|       |:..||....:..| :|..:|
 Worm   110 --------------------------------ATAQF-------VNGMPTAAANQLSTPSPSPAP 135

  Fly   191 VAASLASIPAAVSTSSLEGKSGSEAEAASPTALAAEKRAAASKVEGSATTSGAAARNFATNNLIP 255
            |     .:||:...
 Worm   136 V-----QVPASTDA--------------------------------------------------- 144

  Fly   256 AVPLMTPAVPVPTQRPLEAQDNT-ESEERLAEVRNILEQKRKERVEEEKRMEK--ENELRRRRDG 317
            .:|..|| |..|.|....:|:.| |..|::|..:.:||||:::..|:::..:|  :.|:.:.|:.
 Worm   145 PIPAPTP-VTAPIQSSSTSQEMTRELAEKVARAKALLEQKKQKDAEKKREADKHVKEEMTKAREA 208

  Fly   318 REAQSQQARAKEQELKNMQEQIKRERQEELAA---RERIRAQIAADRAEQAQRF----NTPDISS 375
            ::.:..:|..|         ..|:.:.|:|||   ::||.|||.|||....::|    ||.:.|.
 Worm   209 KQERDAEALVK---------AAKQRKMEKLAAESDKKRILAQIKADREAAQKKFGKLVNTENASE 264

  Fly   376 TTNSVAATAASNVITTDASVSSVDETRLQIRLPGGIQRTKSFPAGEVLATVRVYVRNEMLAASDV 440
            .|.....|.....:.:       |..|||:|||.|....:.||:.:||.::...:|.:...|...
 Worm   265 NTEKKQETTVGKAVPS-------DRCRLQVRLPDGSTFVEEFPSNDVLNSLVEIIRQKPSIAGTT 322

  Fly   441 RDFTLATSYPRREFQTEDEVKTLNELNLVPNAVVLVLTKEQVNRVVQSGGSLMTM-LGTVIWALL 504
              |.:...||||.|..:|..||..|..|.|:..::|:.|...:.......||.|. :..|.|.|.
 Worm   323 --FEIQQPYPRRIFTNDDYSKTFLENQLTPSTALVVIQKSSGSSSNYGSFSLSTQTVSFVTWVLY 385

  Fly   505 TPAAKAFDYINKMGLRPLTQKLSVFMANFRW--PGQRAGLEVYQGDAAARRNMDMFSLRPTPAPG 567
                            |||...::|.....|  .|:       |.|:.:::|
 Worm   386 ----------------PLTAFWNIFCGMIGWNSTGK-------QQDSKSKKN------------- 414

  Fly   568 YEYDGASTEQTGGSAERPTPQNQPGPGNTPPAHNTSQASASQSQQFQQRPGGYQPPKYGDSNIRR 632
               ||.||  :|.|..:|..:..|                 :|.:.::|           .|:..
 Worm   415 ---DGPST--SGQSGSQPQRRGMP-----------------RSAEVRRR-----------GNVAG 446

  Fly   633 LQDTKKDEKDKDKATYNGNSTQ 654
            |::..:|:.: ::|::||||||
 Worm   447 LENPNEDDPE-ERASFNGNSTQ 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8042	NP_648165.1	PRK10263	<165..>369	CDD:236669	44/214 (21%)
		TPH	<269..>367	CDD:464007	29/103 (28%)
		Ubl1_cv_Nsp3_N-like	399..476	CDD:475130	26/76 (34%)
ubxn-4	NP_001370812.1	PRK05641	85..>159	CDD:235540	27/185 (15%)
		tolA_full	<167..>252	CDD:274303	26/93 (28%)
		UBX_UBXN4	282..358	CDD:340534	26/77 (34%)