DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8042 and ubxn-1

DIOPT Version :9

Sequence 1:	NP_648165.1	Gene:	CG8042 / 38886	FlyBaseID:	FBgn0027554	Length:	656	Species:	Drosophila melanogaster
Sequence 2:	NP_490978.1	Gene:	ubxn-1 / 171804	WormBaseID:	WBGene00017733	Length:	299	Species:	Caenorhabditis elegans

Alignment Length:	214	Identity:	75/214 - (35%)
Similarity:	112/214 - (52%)	Gaps:	27/214 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 RPLEAQDNTESEERLAEVRNILE-----QKRKERVEEEKRMEKENELRRRRDGREAQSQQARAKE 329
            :||.|      ||:.|:|..|.|     |.:|.::|.|:..|||.  :||.||:...|.:..|::
Worm   102 KPLTA------EEKAAKVLEIREKIKVHQAKKAKLEAEENREKEK--KRREDGKAMISHKEAARD 158

  Fly   330 QELKNMQEQIKRERQEELAARERIRAQIAADR-AEQAQRFNTPDISSTTNSVAATAASNVITTDA 393
            :|::...:..:||:.|:..||:|:..||..|: |.:|:....|    ...:..|.:|:.|    |
Worm   159 REIREAAQDRRREKNEDEIARKRVLEQIRLDKEARKAKASGQP----VPEAKPAPSAAPV----A 215

  Fly   394 SVSSVDETRLQIRLPGGIQRTKSFPAGEVLATVRVYVRNEMLAASDVRDFTLATSYPRREFQTED 458
            .......|.||.||..|....:.|.|.|.||.||.:|  |...|:.| .|||.|.:||:.| |||
Worm   216 PPKDYSTTTLQFRLLDGQTVRQQFEANEPLAMVRAWV--ETNHANGV-PFTLMTPFPRKVF-TED 276

  Fly   459 EVKT-LNELNLVPNAVVLV 476
            ::.| |..|||||:|.|::
Worm   277 DMGTPLKVLNLVPSANVIL 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8042	NP_648165.1	DUF3682	170..337	CDD:289231	23/71 (32%)
		GBP_C	<272..367	CDD:303769	33/100 (33%)
		coiled coil	342..353	CDD:293879	4/10 (40%)
		UBQ	399..476	CDD:294102	36/77 (47%)
ubxn-1	NP_490978.1	UBA_like_SF	1..36	CDD:328731
		Neuromodulin_N	<86..>197	CDD:331332	34/102 (33%)
		SAKS1_UBX	219..297	CDD:176367	36/81 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.759104	Normalized mean entropy	S3959
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2329
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.890