DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RNaseX25 and Rnaset2b

DIOPT Version :9

Sequence 1:	NP_523966.2	Gene:	RNaseX25 / 38885	FlyBaseID:	FBgn0010406	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	NP_080887.1	Gene:	Rnaset2b / 68195	MGIID:	3702087	Length:	259	Species:	Mus musculus

Alignment Length:	246	Identity:	75/246 - (30%)
Similarity:	115/246 - (46%)	Gaps:	37/246 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 HNWDVLIFTQQWPVTTCYHWREENPDQECSLPQKKEFWTIHGIWPTKLHQMGPNFCNNSANFDPS 138
            |.|..||.||.||.|.|   :|.|..|: ||    ::|||||:||.:...     ||.|.:|:..
Mouse    37 HEWKKLILTQHWPPTVC---KEVNSCQD-SL----DYWTIHGLWPDRAED-----CNQSWHFNLD 88

  Fly   139 KLNPIEDRLETFWPDLKGMDST-EWLWKHEWQKHGTCAMLVEELDNELKYFEQGLTWREEYIMSR 202
            ::..:...::.:|||:....|. ...|||||.||||||..|:.|::|.|||.:.|...::..::.
Mouse    89 EIKDLLRDMKIYWPDVIHRSSNRSQFWKHEWVKHGTCAAQVDALNSEKKYFGKSLDLYKQIDLNS 153

  Fly   203 ILDASDIHPDSN-NTVAAINNAIVKALGKNPSIHCLY-DGKHGISYLSEIRICFSK-SLELIDCD 264
            :|....|.|..| ..:|...:|:.:..|..|.|.||. :....:..:.:|.:||:| .|.|.:|
Mouse   154 VLQKFGIKPSINYYQLADFKDALTRIYGVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNC- 217

  Fly   265 GIKQGD----------AVPVGVPGGTIITNCHIGSLVHYPSLVPPLQRKSH 305
             .:.|:          |:.....|..:   |..|     |...||..:..|
Mouse   218 -TEPGEQLSSRQEAWLAMEASTHGMMV---CEDG-----PIFYPPPTKTQH 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RNaseX25	NP_523966.2	Ribonuclease_T2	80..256	CDD:278852	59/178 (33%)
Rnaset2b	NP_080887.1	RNase_T2_euk	39..221	CDD:238512	65/196 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846152
Domainoid	1	1.000	109	1.000	Domainoid score	I6359
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31190
Inparanoid	1	1.050	113	1.000	Inparanoid score	I4838
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54860
OrthoDB	1	1.010	-	-		D580789at33208
OrthoFinder	1	1.000	-	-		FOG0002105
OrthoInspector	1	1.000	-	-		otm44255
orthoMCL	1	0.900	-	-		OOG6_101324
Panther	1	1.100	-	-	LDO	PTHR11240
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1394
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.870