DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment exex and YOX1

DIOPT Version :9

Sequence 1:	NP_648164.1	Gene:	exex / 38884	FlyBaseID:	FBgn0041156	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_013685.1	Gene:	YOX1 / 854981	SGDID:	S000004489	Length:	385	Species:	Saccharomyces cerevisiae

Alignment Length:	230	Identity:	56/230 - (24%)
Similarity:	91/230 - (39%)	Gaps:	33/230 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   299 SPSPDGMSRSESPTSSHRSS------PPISPGCEDQQQPHGALHPQHLSM--RMSDFHDEFKKPI 355
            |.||...|.:...||.|...      ||::......:....||.....|:  ..|.:.|:..|..
Yeast    21 SSSPVSPSFTNPRTSFHLDDRGTIKLPPLNTSINRPRSVESALRHTVTSLHENSSAYGDDMLKHT 85

  Fly   356 PPHSPIRPQ--------D--------FPLYAGGHPYQLLAQGGSAFHRPLDPSGKPIPIPMGHNF 404
            ...|.:..|        |        .||.:....|.:.::..... .||. :.|.|.||....
Yeast    86 QSDSALSSQLNSSQETVDESHENLLLTPLNSKKRDYSVSSKKNDIL-TPLS-AAKSIIIPSASK- 147

  Fly   405 MPSQLQFEFLARAGMLHHRIPELAAYPHHAILGKTRRPRTAFTSQQLLELEKQFKQNKYLSRPKR 469
             ..:..|.|:..:   ....|:......:|.|.:.:|.||  :||:|..|:.:|::....|:.||
Yeast   148 -EKRRAFAFITHS---QETFPKKEPKIDNAPLARRKRRRT--SSQELSILQAEFEKCPAPSKEKR 206

  Fly   470 FEVASGLMLSETQVKIWFQNRRMKWKRSKKAQQEA 504
            .|:|....::|..|:|||||:|...||.:.|..::
Yeast   207 IELAESCHMTEKAVQIWFQNKRQAVKRQRIATSKS 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeobox	442..495	CDD:278475	20/52 (38%)
YOX1	NP_013685.1	COG5576	126..267	CDD:227863	35/125 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I2937
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910