DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment exex and hoxa3a

DIOPT Version :9

Sequence 1:	NP_648164.1	Gene:	exex / 38884	FlyBaseID:	FBgn0041156	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_571609.1	Gene:	hoxa3a / 58049	ZFINID:	ZDB-GENE-000823-3	Length:	411	Species:	Danio rerio

Alignment Length:	245	Identity:	75/245 - (30%)
Similarity:	103/245 - (42%)	Gaps:	57/245 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   273 QAAASAAGGISEQEALQRIRDSREYDSPSPDGMSRSESPTSSHRSSPPISPG-------CEDQQQ 330
            |:|.......|:|:.||.:....||..|            :....||.||.|       .|..||
Zfish    19 QSANGLGYDASQQQYLQALHAESEYHRP------------ACSLQSPGISAGLHTSNEMSEVCQQ 71

  Fly   331 PHGALHPQHLSMRMSDFHDEFKKPIPPHSPIRPQDFPLYAGGHPYQLLAQGGSAFHRPLDPSGKP 395
            .:|.      ...::|..|..:.|..|..|..|...         ..:....||...|:..|  |
Zfish    72 INGT------QATVTDTSDNKQPPTAPSGPSSPSSL---------NQIPNIDSAAKNPVHVS--P 119

  Fly   396 IPIPMGHNF--MPSQLQ---------FEFLARAGMLHHRIPELAAYPHHAILGKTRRPRTAFTSQ 449
            .|....|.|  |....|         ....:.||  ..:.|..:|        .::|.|||:||.
Zfish   120 TPSTRKHIFPWMKESRQNTKQKSCSIISVESCAG--RQKSPPGSA--------ASKRARTAYTSA 174

  Fly   450 QLLELEKQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKK 499
            ||:||||:|..|:||.||:|.|:|:.|.|:|.|:||||||||||:|:.:|
Zfish   175 QLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeobox	442..495	CDD:278475	34/52 (65%)
hoxa3a	NP_571609.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	79..126		12/57 (21%)
		Antp-type hexapeptide	127..132		1/4 (25%)
		Homeobox	168..220	CDD:278475	34/51 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	223..250		1/2 (50%)
		DUF4074	347..409	CDD:290032
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910