DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment exex and hoxd1

DIOPT Version :9

Sequence 1:	NP_648164.1	Gene:	exex / 38884	FlyBaseID:	FBgn0041156	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001016678.1	Gene:	hoxd1 / 549432	XenbaseID:	XB-GENE-482731	Length:	301	Species:	Xenopus tropicalis

Alignment Length:	263	Identity:	74/263 - (28%)
Similarity:	93/263 - (35%)	Gaps:	108/263 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 CEDQQ-----QPH---GALHP-----------QHLSMRMSD------FHDEFKKPIPP------H 358
            |...|     ||:   ||.||           .|.:...|.      ..|...:|.||      |
Frog    21 CRSDQRNMTLQPYPGSGADHPFMPVGGVPGSVAHQASHQSPALYAPCSLDVAYEPPPPSDYSFLH 85

  Fly   359 SPIRPQDFPLY--------AGGH-PYQLLAQGGSAFHRPLDPSGKPIPIPMGHNFMPSQLQFEFL 414
            |   ..|:..|        .||| ||     |.|.|     |..       |...:..||.:..|
Frog    86 S---STDYDYYGSNHLVEETGGHIPY-----GSSVF-----PGN-------GSYILNGQLSYRTL 130

  Fly   415 AR------------------AGMLHHRIPELAAYPHHAI------------LGKTRRP------- 442
            ..                  .|.|....|....||..|.            :...|.|
Frog   131 GEETQMAQIAQCKEPLEVYPGGNLQSISPSPGTYPKPASPASDTHVSTFDWMKVKRNPPKKSLQS 195

  Fly   443 -----------RTAFTSQQLLELEKQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKR 496
                       ||.||::||.||||:|..||||:|.:|.|:|:.|.|::|||||||||||||.|:
Frog   196 EYGVASPPCTVRTNFTTKQLTELEKEFHFNKYLTRARRIEIANSLQLNDTQVKIWFQNRRMKQKK 260

  Fly   497 SKK 499
            .::
Frog   261 RER 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeobox	442..495	CDD:278475	35/70 (50%)
hoxd1	NP_001016678.1	Antp-type hexapeptide. /evidence=ECO:0000255	178..183		0/4 (0%)
		Homeobox	207..260	CDD:365835	34/52 (65%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	255..301		4/9 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910