DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment exex and hoxb3

DIOPT Version :9

Sequence 1:	NP_648164.1	Gene:	exex / 38884	FlyBaseID:	FBgn0041156	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001015971.1	Gene:	hoxb3 / 548725	XenbaseID:	XB-GENE-482576	Length:	386	Species:	Xenopus tropicalis

Alignment Length:	196	Identity:	61/196 - (31%)
Similarity:	82/196 - (41%)	Gaps:	53/196 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 PTSSHRSSPPISPGCEDQQQPHGALHPQHLSMRMSDFHDEFKKPIPPH-----SPIRPQDFPLYA 370
            |..|...|.|:||........:.:.....||           ||.|..     ||...|.||...
Frog    71 PNLSSEQSQPLSPTANPSSNTNSSSSQASLS-----------KPSPAKSQASGSPASKQIFPWMK 124

  Fly   371 GGHPYQLLAQGGSAFHRPLDPSGKPIPIPMGHNFMPSQLQFEFLARAGMLHHRIPELAAYPHHAI 435
            ...      |.......|..|:.:    ..|.:..|                  |..:|
Frog   125 ESR------QNSKQKSSPPAPAAE----SCGGDRSP------------------PGSSA------ 155

  Fly   436 LGKTRRPRTAFTSQQLLELEKQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKKA 500
               ::|.|||:||.||:||||:|..|:||.||:|.|:|:.|.|||.|:||||||||||:|:.:|.
Frog   156 ---SKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKV 217

  Fly   501 Q 501
            :
Frog   218 K 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeobox	442..495	CDD:278475	35/52 (67%)
hoxb3	NP_001015971.1	Homeobox	160..212	CDD:306543	35/51 (69%)
hoxb3	NP_001015971.1	DUF4074	325..384	CDD:315871
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910