DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment exex and gsx1

DIOPT Version :9

Sequence 1:NP_648164.1 Gene:exex / 38884 FlyBaseID:FBgn0041156 Length:525 Species:Drosophila melanogaster
Sequence 2:NP_001012251.1 Gene:gsx1 / 449875 ZFINID:ZDB-GENE-041008-135 Length:243 Species:Danio rerio


Alignment Length:230 Identity:67/230 - (29%)
Similarity:96/230 - (41%) Gaps:72/230 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   303 DGMSRSESPTSSHRSSPPISPGCEDQQQPHGALHPQHLSMRMSDFHDEFKK-------------- 353
            |.:...|:......:|||:.|         .|:||.|....:|......:|              
Zfish     8 DSLILRENSEKGTENSPPLFP---------YAVHPSHPLHSLSAGSCHSRKAGLLCFCPLCVTSQ 63

  Fly   354 --PIPPHSPIRPQDFPLYAGGHPYQLLAQ-----------GGSAFHRPLDPSGKPIPIPMGHNFM 405
              |.||..|:....||.:...:.:..|::           .||..::    :..|:|.|...:.:
Zfish    64 LHPSPPALPLIKASFPAFGTQYCHSALSRQHSTSSGVNLNSGSGLYQ----AAYPVPDPRQFHCI 124

  Fly   406 -----PSQLQFEFLARAGMLHHRIPELAAYPHHAILGKTRRPRTAFTSQQLLELEKQFKQNKYLS 465
                 .||||                           .::|.||||||.||||||::|..|.|||
Zfish   125 SIENSSSQLQ---------------------------SSKRMRTAFTSTQLLELEREFTSNMYLS 162

  Fly   466 RPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKKA 500
            |.:|.|:|:.|.|||.||||||||||:|.|:..|:
Zfish   163 RLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKS 197

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
exexNP_648164.1 Homeobox 442..495 CDD:278475 36/52 (69%)
gsx1NP_001012251.1 Homeobox 140..192 CDD:278475 36/51 (71%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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