Protein Alignment exex and cdx1

DIOPT Version :10

• Sequence 1: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_989416.1
• Gene: cdx1 / 395055
• XenbaseID: XB-GENE-485396
• Length: 262
• Species: Xenopus tropicalis
• Alignment Length: 244
• Identity: 69/244 - (28%)
• Similarity: 97/244 - (39%)
• Gaps: 81/244 - (33%)

  Fly   326 EDQQQPHGALHPQHLSMRMSDFHDEFKKPIPPHSPIRPQDFPLY--------------AGG---- 372
            ::...|:...|| .|::...::     .|.||    :..|||.|              .||
 Frog    10 DNNMYPNPVRHP-GLNLNPQNY-----VPAPP----QYSDFPSYHHVPGINSDPHHGQPGGTWSS 64

  Fly   373 --------HPYQLLAQG-GSAFHRPLDPSGKPI---PI-PMGHNFMPSQLQ-------------- 410
                    |||   ..| |::...|...|..|.   |: |.|...:|..|.
 Frog    65 YTPSREDWHPY---GPGPGASSANPAQISFSPSDYNPVQPPGPGLLPPSLNSSVSPLSPSAQRRN 126

  Fly   411 -FEFLARAGMLHHRIPELAAYPHHAILGKTR---RPRTAFTSQQLLELEKQFKQNKYLSRPKRFE 471
             :|::.|.|     :|......     ||||   :.|..:|..|.|||||:|..::|::..::.|
 Frog   127 LYEWMRRTG-----VPTSTNSN-----GKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAE 181

  Fly   472 VASGLMLSETQVKIWFQNRRMKWKRSKKAQQEAKERAKANQQQQQQQQT 520
            :|:.|.|:|.||||||||||.|         |.|...|..|||.||..|
 Frog   182 LAASLALTERQVKIWFQNRRAK---------ERKVNKKKMQQQSQQAST 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeodomain	440..496	CDD:459649	27/58 (47%)
cdx1	NP_989416.1	Caudal_act	13..141	CDD:461413	30/145 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..120		16/80 (20%)
		Homeodomain	151..206	CDD:459649	27/63 (43%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	152..173		9/20 (45%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	191..202		9/10 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..262		10/28 (36%)