Protein Alignment exex and HOXD8

DIOPT Version :9

• Sequence 1: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_062458.1
• Gene: HOXD8 / 3234
• HGNCID: 5139
• Length: 290
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 88/306 - (28%)
• Similarity: 117/306 - (38%)
• Gaps: 93/306 - (30%)

  Fly   268 AAAAAQAAASAA--------------GG--ISEQEALQRIRDSREYDSPSPDGMSRSESPTSSHR 316
            |||||.|||..|              ||  .:...|||...:|......:|     .::....|.
Human    15 AAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAGFPHAP-----PQAHAHPHP 74

  Fly   317 SSPPISPGC---EDQQQPHGALHPQHLSMRMSDFHDEFKKPIPPHSPIRPQDFPLYAGGHPYQLL 378
            |.||...||   |.:.|.:  .||...|...:   .:...|.|||.|..|...|.
Human    75 SPPPSGTGCGGREGRGQEY--FHPGGGSPAAA---YQAAPPPPPHPPPPPPPPPC---------- 124

  Fly   379 AQGGSAFHRPLDPSGKPIPIPMGHNFMPSQLQFEFLARAGMLHHRIPELAAYPH----------- 432
              ||.|.|      |:|... .|::.:..|..|.....|        ||..||.
Human   125 --GGIACH------GEPAKF-YGYDNLQRQPIFTTQQEA--------ELVQYPDCKSSSGNIGED 172

  Fly   433 -------------------HAILGKTRRPRTAFTSQQLLELEKQFKQNKYLSRPKRFEVASGLML 478
                               .|..|: ||.|..::..|.|||||:|..|.||:|.:|.||:..|.|
Human   173 PDHLNQSSSPSQMFPWMRPQAAPGR-RRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALAL 236

  Fly   479 SETQVKIWFQNRRMKWKRSKK------AQQEAKERAKANQQQQQQQ 518
            :|.||||||||||||||:...      ::||.|:.....:.|:.::
Human   237 TERQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEE 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeobox	442..495	CDD:278475	30/52 (58%)
HOXD8	NP_062458.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..127		20/88 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..200		3/39 (8%)
		Homeobox	201..253	CDD:278475	30/51 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..290		4/28 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810