Protein Alignment exex and HOXD1

DIOPT Version :9

• Sequence 1: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_078777.1
• Gene: HOXD1 / 3231
• HGNCID: 5132
• Length: 328
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 101/421 - (23%)
• Similarity: 145/421 - (34%)
• Gaps: 152/421 - (36%)

  Fly    93 YTPALSPGGAQD---SSQTESGQSSQMPLLVAP-MPVGTGPPHSHPPPPHPRLYVEGFPPPHHVP 153
            |....|.||...   |...:..:|...|:.:.| .|:|.|          ...:|...|.....|
Human     7 YVSCSSSGGVGGDVLSLAPKFCRSDARPVALQPAFPLGNG----------DGAFVSCLPLAAARP 61

  Fly   154 HPHPALGTYPLPRLPLMLPANPPGVPSGAAAPPPVSPQPAANHLSHSGATMATTTLLPPAQSQPK 218
            .|                  :||..|:..:.|||.:||
Human    62 SP------------------SPPAAPARPSVPPPAAPQ--------------------------- 81

  Fly   219 KSFCIDALLAKSQHQSGEPQPIIVDDRLAALHYARDQAELNHAFVTASNAAAAAQAAASAAGGIS 283
                                            ||  |..|..|:  ...||.||.|..:..|.:.
Human    82 --------------------------------YA--QCTLEGAY--EPGAAPAAAAGGADYGFLG 110

  Fly   284 EQEALQRIRDSREYDSPSPDGMSRSESPTSSHRSSPPISPGCEDQQQPHGALHPQHLSMRMSDFH 348
            ...|         ||.|...|.:..:..:..|.::..:..|        |.      |..:|...
Human   111 SGPA---------YDFPGVLGRAADDGGSHVHYATSAVFSG--------GG------SFLLSGQV 152

  Fly   349 D--EFKKPIPPHSPIRPQDFP----LYAGGHP--YQLLAQGGSAFHRPLDP-SGKPIPIPMGHNF 404
            |  .|.:|.|         ||    ..|.|||  :|..:.....:.:.:.| ||.|...
Human   153 DYAAFGEPGP---------FPACLKASADGHPGAFQTASPAPGTYPKSVSPASGLPAAF------ 202

  Fly   405 MPSQLQFEFLARAGMLHHRIPEL-AAYPHHAILGKTRRPRTAFTSQQLLELEKQFKQNKYLSRPK 468
              |..::..:.|......::.|. ||.|..||       ||.|:::||.||||:|..||||:|.:
Human   203 --STFEWMKVKRNASKKGKLAEYGAASPSSAI-------RTNFSTKQLTELEKEFHFNKYLTRAR 258

  Fly   469 RFEVASGLMLSETQVKIWFQNRRMKWKRSKK 499
            |.|:|:.|.|::|||||||||||||.|:.::
Human   259 RIEIANCLHLNDTQVKIWFQNRRMKQKKRER 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeobox	442..495	CDD:278475	33/52 (63%)
HOXD1	NP_078777.1	Antp-type hexapeptide	204..209		0/4 (0%)
		Homeobox	233..285	CDD:278475	33/51 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..328

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810