DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment exex and HOXC8

DIOPT Version :9

Sequence 1:	NP_648164.1	Gene:	exex / 38884	FlyBaseID:	FBgn0041156	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_073149.1	Gene:	HOXC8 / 3224	HGNCID:	5129	Length:	242	Species:	Homo sapiens

Alignment Length:	128	Identity:	47/128 - (36%)
Similarity:	68/128 - (53%)	Gaps:	28/128 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   401 GH---NFMPSQLQFEFLARAGMLHHRIPELAAYPHHAILGKTRRPRTAFTSQQLLELEKQFKQNK 462
            ||   |..|| |.|.::.               ||..  |: |..|..::..|.|||||:|..|.
Human   127 GHLNQNSSPS-LMFPWMR---------------PHAP--GR-RSGRQTYSRYQTLELEKEFLFNP 172

  Fly   463 YLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKK------AQQEAKERAKANQQQQQQQQ 519
            ||:|.:|.||:..|.|:|.||||||||||||||:...      |:.|.|...:.|::::::::
Human   173 YLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEE 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeobox	442..495	CDD:278475	30/52 (58%)
HOXC8	NP_073149.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	114..154		11/45 (24%)
		Antp-type hexapeptide	138..143		1/4 (25%)
		Homeobox	153..205	CDD:306543	30/51 (59%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	206..242		4/30 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810