Protein Alignment exex and HOXB9

DIOPT Version :10

• Sequence 1: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_076922.1
• Gene: HOXB9 / 3219
• HGNCID: 5120
• Length: 250
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 71/253 - (28%)
• Similarity: 91/253 - (35%)
• Gaps: 87/253 - (34%)

  Fly   314 SHRS--SPPI---SPGCEDQQQPHGALHPQHLSMRMSDFHDEFK------KPIPPHSPIRPQDFP 367
            ||.|  :||.   |......:||.   |.:||......|..:..      .|:.||:
Human    17 SHESEDAPPAKFPSGQYASSRQPG---HAEHLEFPSCSFQPKAPVFGASWAPLSPHA-------- 70

  Fly   368 LYAGGHPYQLLAQGGSAFHRPLDPSGKP-----------IPIPMGHNFMPSQLQFEFLAR----- 416
              :|..|        |.:|..:.|.|.|           .|.|.| ...|.|.|....|.
Human    71 --SGSLP--------SVYHPYIQPQGVPPAESRYLRTWLEPAPRG-EAAPGQGQAAVKAEPLLGA 124

  Fly   417 -AGMLHHRIPELA---AYPHHAILG----------------------------------KTRRPR 443
             ..:|....||.:   :....|:|.                                  .:|:.|
Human   125 PGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHARSSRKKR 189

  Fly   444 TAFTSQQLLELEKQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKKAQ 501
            ..:|..|.|||||:|..|.||:|.:|.|||..|.|||.||||||||||||.|:..|.|
Human   190 CPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQ 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeodomain	440..496	CDD:459649	34/55 (62%)
HOXB9	NP_076922.1	Hox9_act	1..172	CDD:461369	34/176 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..47		8/28 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..182		0/32 (0%)
		Homeodomain	186..242	CDD:459649	34/55 (62%)