Protein Alignment exex and HOXA10

DIOPT Version :10

• Sequence 1: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_061824.3
• Gene: HOXA10 / 3206
• HGNCID: 5100
• Length: 410
• Species: Homo sapiens
• Alignment Length: 501
• Identity: 112/501 - (22%)
• Similarity: 143/501 - (28%)
• Gaps: 197/501 - (39%)

  Fly    50 PPAQDYDQGSNQSTLSP-----RSQITPSPPAASPTHSAATTGSPVSTYTPALSPGGAQDSSQTE 109
            |||.|...|.....|.|     |::      ||||.......|         |.||.      ..
Human    66 PPAADLPYGLQSCGLFPTLGGKRNE------AASPGSGGGGGG---------LGPGA------HG 109

  Fly   110 SGQSSQMPLLVAPMPVGTGPPHSHPPPPHPRLYVEGFPPPHHVPHPHPALGTYPLPRLPLMLPAN 174
            .|.|.....|.||......||...||||..:
Human   110 YGPSPIDLWLDAPRSCRMEPPDGPPPPPQQQ---------------------------------- 140

  Fly   175 PPGVPSGAAAPPPVSPQPAANHLSHSGA--------------------TMATTTLLPPAQSQPKK 219
            ||        |||..||||....|.|.|                    ..||...|.|....|..
Human   141 PP--------PPPQPPQPAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPP 197

  Fly   220 SFCIDALLAKSQHQSGEPQPIIVDDRLAALHYARDQAELNHAFVTASNAAAAAQAAASAAGGISE 284
            ..|   .|..|   ||.|.|                     .:...|.|...|:...|..||..:
Human   198 DGC---ALGTS---SGVPVP---------------------GYFRLSQAYGTAKGYGSGGGGAQQ 235

  Fly   285 QEALQRIRDSREYDSPSPDGMSRSESPTSSHRSSPPISPGCEDQQQPHGALHPQHLSMRMSDFHD 349
            ..|           .|.|     ::.|.......|.::.|..|..:...||..
Human   236 LGA-----------GPFP-----AQPPGRGFDLPPALASGSADAARKERALDS------------ 272

  Fly   350 EFKKPIPPHSPIRPQDFPLYAGGHPYQLLAQGGSAFHRPLDPSGKPIPIPMGHNFMPSQLQFEFL 414
                  ||     |......:||.     :||....|.....:.:..|.|...:
Human   273 ------PP-----PPTLACGSGGG-----SQGDEEAHASSSAAEELSPAPSESS----------- 310

  Fly   415 ARAGMLHHRIPELAAYPHHAILGKT--------------RRPRTAFTSQQLLELEKQFKQNKYLS 465
                         .|.|....||.:              |:.|..:|..|.|||||:|..|.||:
Human   311 -------------KASPEKDSLGNSKGENAANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLT 362

  Fly   466 RPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKKAQQEAKERAKAN 511
            |.:|.|::..:.|::.||||||||||||.|:..:..:..:..|..|
Human   363 RERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFN 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeodomain	440..496	CDD:459649	29/55 (53%)
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..158		29/131 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..339		28/185 (15%)
		Homeodomain	337..393	CDD:459649	29/55 (53%)