Protein Alignment exex and HOXA4

DIOPT Version :9

• Sequence 1: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_002132.3
• Gene: HOXA4 / 3201
• HGNCID: 5105
• Length: 320
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 108/403 - (26%)
• Similarity: 138/403 - (34%)
• Gaps: 135/403 - (33%)

  Fly   142 YVEGFPPPHHVPHPHPALGTYPLPRLPLMLPANPPGVPSGAAAPPPVSPQPAANHLSHSGATMAT 206
            |:|...||......|...|                |...|....|.....||
Human    12 YIEPKFPPFEEYAQHSGSG----------------GADGGPGGGPGYQQPPA------------- 47

  Fly   207 TTLLPPAQSQPKKSFCIDALLAKSQ--HQSGEPQPIIVDDRLAALHYARDQAELNHAFVTASNAA 269
                ||.|..|         |.:.|  |..|..:|       .|.:||..         ||...|
Human    48 ----PPTQHLP---------LQQPQLPHAGGGREP-------TASYYAPR---------TAREPA 83

  Fly   270 AAAQAAASAAGGISEQEALQRIRDSREYDSPSPDGMSRSESPTSSHRSSPPISPGCEDQQQPHGA 334
            ..|.|...|.|..               |:..|.|.....||   .|...|..|..:.:...||
Human    84 YPAAALYPAHGAA---------------DTAYPYGYRGGASP---GRPPQPEQPPAQAKGPAHG- 129

  Fly   335 LHPQHLSMRMSDFHDEFKKP-----IPPHSPIRPQDFPLYAGGHPYQLLAQGGSAFHRPLDPSGK 394
            ||..|:      ...:...|     :||.:|.|.:..|...|      :..||||...||
Human   130 LHASHV------LQPQLPPPLQPRAVPPAAPRRCEAAPATPG------VPAGGSAPACPL----- 177

  Fly   395 PIPIPMGHNFMPSQLQFEFLARAGMLHHRIPELAAYP-----HHAIL------GKTRRPRTAFTS 448
                              .||....|..:..|...||     |.:.:      |:.:|.|||:|.
Human   178 ------------------LLADKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTR 224

  Fly   449 QQLLELEKQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKR-----SKKAQQEAKERA 508
            ||:|||||:|..|:||:|.:|.|:|..|.|||.||||||||||||||:     :.|.:......|
Human   225 QQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASA 289

  Fly   509 KANQQQQQQQQTP 521
            .|....:.|.|:|
Human   290 SAGPPGKAQTQSP 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeobox	442..495	CDD:278475	35/52 (67%)
HOXA4	NP_002132.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..77		20/106 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..168		19/82 (23%)
		Antp-type hexapeptide	194..199		2/4 (50%)
		Homeobox	218..271	CDD:278475	35/52 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	273..320		6/30 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810