DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment exex and Hoxc5

DIOPT Version :9

Sequence 1:	NP_648164.1	Gene:	exex / 38884	FlyBaseID:	FBgn0041156	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001101586.1	Gene:	Hoxc5 / 315341	RGDID:	1307584	Length:	222	Species:	Rattus norvegicus

Alignment Length:	245	Identity:	68/245 - (27%)
Similarity:	103/245 - (42%)	Gaps:	50/245 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 TASNAAAAAQAAAS--AAGGISEQEALQRIRDSREYDSPSPDGMSRSESPTSSHRSSPPISPGCE 326
            |..|..:|::..||  ..||:..         |..:..|:|..........::.|:.|. .|.|.
  Rat    23 TCGNYGSASEVQASRYCYGGLDL---------SITFPPPAPSNSLHGVDMAANPRAHPD-RPACS 77

  Fly   327 DQQQPHGALHPQHLSMRMSDFHDEFKKPIPPHSPIRPQDFPLYAGGHPYQLLAQGGSAFHRPLDP 391
            ....|..||.           .||       .:|:.|..:...|.....:..|:...........
  Rat    78 AAAAPGHALG-----------RDE-------AAPLNPGMYSQKAARPALEERAKSSGEIKEEQAQ 124

  Fly   392 SGKPIPIPMGHNFMPSQLQ-FEFLARAGMLHHRIPELAAYPHHAILGKTRRPRTAFTSQQLLELE 455
            :|:    |.|.:..|:..| :.::.:..|.|..              ..:|.||::|..|.||||
  Rat   125 TGQ----PAGLSQPPAPPQIYPWMTKLHMSHET--------------DGKRSRTSYTRYQTLELE 171

  Fly   456 KQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKR-SKKAQQEA 504
            |:|..|:||:|.:|.|:|:.|.|:|.|:||||||||||||: ||...:||
  Rat   172 KEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKSKEA 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeobox	442..495	CDD:278475	31/52 (60%)
Hoxc5	NP_001101586.1	COG5373	65..>142	CDD:227665	18/99 (18%)
Hoxc5	NP_001101586.1	Homeobox	158..212	CDD:395001	32/53 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810