DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment exex and hoxa2b

DIOPT Version :9

Sequence 1:	NP_648164.1	Gene:	exex / 38884	FlyBaseID:	FBgn0041156	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_571181.1	Gene:	hoxa2b / 30325	ZFINID:	ZDB-GENE-990415-98	Length:	363	Species:	Danio rerio

Alignment Length:	219	Identity:	71/219 - (32%)
Similarity:	93/219 - (42%)	Gaps:	75/219 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   317 SSPPI-----SPGCEDQQQPHGALHPQHLSMRMSDFHDEFKKPIPPHSPIRPQDFPLYAGGHPYQ 376
            |.||:     |...:.....|..|.|           ..|::.||..:|          |.||
Zfish    24 SFPPVGDAFQSSSIKSSTLSHSTLIP-----------PPFEQTIPSLNP----------GSHP-- 65

  Fly   377 LLAQGGSAFHRP-LDPSGK-PIP---IPMGHNFM-------------------PSQLQFEFLARA 417
                   ...|| .:|:|. |:|   :|..:.:|                   |..|.|.
Zfish    66 -------RHSRPKQNPNGSCPLPAASLPPEYPWMKEKKASKKNQTTSTAATTDPGPLYFS----- 118

  Fly   418 GMLHHRIPELAAYPHHAILGKTRRPRTAFTSQQLLELEKQFKQNKYLSRPKRFEVASGLMLSETQ 482
               ....||::    ....|.|||.|||:|:.|||||||:|..||||.||:|.|:|:.|.|:|.|
Zfish   119 ---PQGSPEIS----DGGSGATRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQ 176

  Fly   483 VKIWFQNRRMKWKRSKKAQQEAKE 506
            ||:||||||||.||    |.:.||
Zfish   177 VKVWFQNRRMKHKR----QTQCKE 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeobox	442..495	CDD:278475	35/52 (67%)
hoxa2b	NP_571181.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	42..132		23/131 (18%)
		Antp-type hexapeptide	88..93		0/4 (0%)
		Homeobox	137..189	CDD:278475	35/51 (69%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	186..218		7/15 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	245..279
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810