Protein Alignment exex and GSX1

DIOPT Version :9

• Sequence 1: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_663632.1
• Gene: GSX1 / 219409
• HGNCID: 20374
• Length: 264
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 84/275 - (30%)
• Similarity: 116/275 - (42%)
• Gaps: 74/275 - (26%)

  Fly   291 IRDSREYDSPSPDGMSRSESPTSSHRSSPP-----ISPG-CEDQQQPHGALHPQHLSMRMSDFHD 349
            :|::.|  ..:|:|   |..|...:...||     :||| |..::.  |.|....|.:..|..|.
Human    12 LREAGE--KKAPEG---SPPPLFPYAVPPPHALHGLSPGACHARKA--GLLCVCPLCVTASQLHG 69

  Fly   350 EFKKPIPPHSPIRPQDFPLYAGGHPYQLLAQGGSAFHRPLDPSGKPIPIPMGHNFMPSQLQFEFL 414
               .|.||..|:....||      |:     |....|.||......:...:.|.  |:.     .
Human    70 ---PPGPPALPLLKASFP------PF-----GSQYCHAPLGRQHSAVSPGVAHG--PAA-----A 113

  Fly   415 ARAGMLHHRIPELAAYP------HHAI--------LGKTRRPRTAFTSQQLLELEKQFKQNKYLS 465
            |.|..|:.     .:||      .|.|        |..::|.||||||.||||||::|..|.|||
Human   114 AAAAALYQ-----TSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLS 173

  Fly   466 RPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKK-----------------AQQEAK----ERAK 509
            |.:|.|:|:.|.|||.||||||||||:|.|:..|                 |.|..|    ..||
Human   174 RLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAK 238

  Fly   510 ANQQQQQQQQTPSAA 524
            .::...:...:||::
Human   239 CSEDDDELPMSPSSS 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeobox	442..495	CDD:278475	36/52 (69%)
GSX1	NP_663632.1	SNAG domain. /evidence=ECO:0000250	1..20		2/9 (22%)
		Homeobox	151..204	CDD:395001	36/52 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..264		10/53 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810