Protein Alignment exex and EVX1

DIOPT Version :10

• Sequence 1: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001980.1
• Gene: EVX1 / 2128
• HGNCID: 3506
• Length: 407
• Species: Homo sapiens
• Alignment Length: 348
• Identity: 85/348 - (24%)
• Similarity: 118/348 - (33%)
• Gaps: 138/348 - (39%)

  Fly   158 ALGTYPLPRLPLMLPANPPGVPSGAAAPPPVSPQPAANHLSHSGATMATTTLLPPAQSQPKKSFC 222
            |:|: |||..|..:      ||.|..:|..|                      |||
Human    30 AVGS-PLPEPPEKM------VPRGCLSPRAV----------------------PPA--------- 56

  Fly   223 IDALLAKSQHQSG---EPQPIIVDDRLAALHYARDQAELNHAFVTASNAAAAAQAAASAAGGISE 284
                   ::.:.|   |.:|:   |.||.               :|:...|..|.|.:|..|...
Human    57 -------TRERGGGGPEEEPV---DGLAG---------------SAAGPGAEPQVAGAAMLGPGP 96

  Fly   285 QEALQRIRDSREYDSPSPDGMSRSESPTSSHRSSPPISPGCEDQQQPHGALHPQHLSMRMSDFHD 349
                         .:||.|.:|....|:||...                           |||::
Human    97 -------------PAPSVDSLSGQGQPSSSDTE---------------------------SDFYE 121

  Fly   350 EFKKPIPPHSPIRPQDFPLYAGGHPYQLLA--QGGSAFHRPLDPSGKPIPIPMGHNFMPSQLQFE 412
            |.:....|.......::....|.....|:.  .|||...:....||       |..   ||....
Human   122 EIEVSCTPDCATGNAEYQHSKGSGSEALVGSPNGGSETPKSNGGSG-------GGG---SQGTLA 176

  Fly   413 FLARAGMLHHRIPELAAYPHHAILGKTRRPRTAFTSQQLLELEKQFKQNKYLSRPKRFEVASGLM 477
            ..|...|                    ||.|||||.:|:..|||:|.:..|:|||:|.|:|:.|.
Human   177 CSASDQM--------------------RRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALN 221

  Fly   478 LSETQVKIWFQNRRMKWKRSKKA 500
            |.||.:|:||||||||.||.:.|
Human   222 LPETTIKVWFQNRRMKDKRQRLA 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeodomain	440..496	CDD:459649	32/55 (58%)
EVX1	NP_001980.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..120		35/192 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..179		10/51 (20%)
		Homeodomain	184..240	CDD:459649	32/55 (58%)