Protein Alignment exex and Pdx1

DIOPT Version :10

• Sequence 1: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_032840.1
• Gene: Pdx1 / 18609
• MGIID: 102851
• Length: 284
• Species: Mus musculus
• Alignment Length: 266
• Identity: 83/266 - (31%)
• Similarity: 112/266 - (42%)
• Gaps: 78/266 - (29%)

  Fly   283 SEQE---ALQRIRDSREYD-SPSPDGMSRSESPTSSHRSSPPISPGCEDQQQPHGALHPQHLSMR 343
            ||::   |.|..:|...:. .|.|:..:...:.....|..||..|             ||..|..
Mouse     3 SEEQYYAATQLYKDPCAFQRGPVPEFSANPPACLYMGRQPPPPPP-------------PQFTSSL 54

  Fly   344 MSDFHDEFKKPIPPHSPIRPQDFPLYAGGHP------YQLLAQGGSAFHRPLDPSGKPIPIPMGH 402
            .|     .::..||  .|.|.:.|..|...|      :.|.||.|.| |.|      |.|.|.|.
Mouse    55 GS-----LEQGSPP--DISPYEVPPLASDDPAGAHLHHHLPAQLGLA-HPP------PGPFPNGT 105

  Fly   403 N----FMPSQLQFEFLARAGMLHHRIPELAAYPHHAILG------------KTRRPRTAFTSQQL 451
            .    ..|:::|..|           |.:.:...||..|            :.:|.|||:|..||
Mouse   106 EPGGLEEPNRVQLPF-----------PWMKSTKAHAWKGQWAGGAYTAEPEENKRTRTAYTRAQL 159

  Fly   452 LELEKQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKKAQQEAKERAKANQQQQQ 516
            |||||:|..|||:|||:|.|:|..|.|:|..:||||||||||||:     :|.|:|:..
Mouse   160 LELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKK-----EEDKKRSSG------ 213

  Fly   517 QQQTPS 522
               |||
Mouse   214 ---TPS 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exex	NP_648164.1	Homeodomain	440..496	CDD:459649	36/55 (65%)
Pdx1	NP_032840.1	Transactivation domain. /evidence=ECO:0000250	13..73		16/79 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..116		27/112 (24%)
		Antp-type hexapeptide	119..124		2/15 (13%)
		Homeodomain	148..204	CDD:459649	36/55 (65%)
		Nuclear localization signal	198..204		5/5 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..284		8/29 (28%)